Jacqueline Woolley, Chair The University of Texas at Austin, SEA 4.212, Austin, TX 78712 • (512) 475-7596
Behavioral Neuroscience Seminar - "TOR and NO as regulators of brain vascular function in a mouse model of Alzheimer's disease"
Wed, April 24, 2013 • 3:00 PM - 4:30 PM • SEA 4.244
Dr. Veronica Galvan
Department of Physiology and The Barshop Institute for Longevity and Aging Studies
University of Texas Health Science Center at San Antonio
phone: (210) 562-5029/6002
RESEARCH INTERESTS: Aging is, by far, the greatest risk factor for neurodegenerative diseases. Very little is known about the molecular mechanisms that connect aging to brain diseases like Alzheimer's. With the discovery of genetic pathways that can be precisely manipulated to delay the aging process, hypothesis-driven experiments can be performed to understand brain aging, and to create therapeutic strategies targeting the pathways that drive it. My research group is primarily focused on attempting to identify the molecular pathways that drive brain aging, and to determine how these processes lead to Alzheimer's disease and other neurodegenerations. Our hypothesis is that the pathways that control organismal aging can be harnessed to manipulate brain aging and thus delay or prevent brain age-associated diseases. In addition to experiments in mouse models, we routinely test potential drug candidate molecules with neurobehavioral, cellular and molecular biology tools to determine the effect of these interventions on cognitive outcomes, and to define the mechanisms involved. A second interest of my lab is to investigate the potential of modulating neurogenesis or using neuronal precursor cells for the treatment of brain injury and neurodegeneration.
A simple pill developed to slow down aging!?
Check out this video interview with Dr Galvan about her research: