T C 357 • Molecular Biology, Problem Solving, and Epidemiology
12:00 PM-3:00 PM
This course shows you how to combine molecular biology, problem solving, and epidemiology into creative and testable research ideas about diseases. The first two-thirds of the semester include lectures, class exercises, information gathering, and the generation of ideas. Lecture topics include how to use problem solving to get creative research ideas and how to think like a disease to get clues about causation. You will also learn to use research data bases such as PubMed, OMIM, and eMedicine, as well as research tools such as GeneCards, Human and Mouse Genome mapping sites, analytic programs such as BLAST and BIND, amino acid analysis, 3-Dimensional modeling, and others. The exact tools that we will cover will be determined in part by the ideas that we generate in the class project. I intend for this course to be interesting and fun. The goal is not for you to become an expert in any particular field, but rather to introduce you to methods that can guide your future study. This course is probably the only one of its kind in the country and should increase your attractiveness to medical schools and research oriented graduate programs.
Readings will arise as we pursue ideas for the class project and range from popular overviews to original research literature. Additional readings involve manuals, websites, and instructions for using various databases and analytic programs (e.g., eMedicine, OMIM, Human Genome).