This paper will consider the work of the Marcus Garvey movement of the 1920s, in relation to the psychological well-being of peoples of African descent globally. The Universal Negro Improvement Association (UNIA) had chapters in Africa, Europe, Caribbean and Americas, espousing the ideology of psychological betterment and freedom for Africans. There are many lessons to learn from Marcus Garvey in the 21st Century, and one such is the need for greater cooperation between peoples of African descent who continue to cope with the ravages and legacy of European colonialism and dsyfunctional African leadership. The plight of the African continent in terms of HIV/AIDS, poverty and widespread disunity makes Marcus Garvey's UNIA movement and related themes arguably more relevant than ever before. Indeed, what can we learn from the past to enhance the contemporary psychological development of Africans everywhere? This paper will discuss this question via consideration of the themes and perspectives of Marcus Garvey.