Zoo 317 Heredity, Evolution and Society

Lecture 7 Cummings 4: 85-95
PEDIGREE ANALYSIS: DOMINANT; SEX-LINKED

I. Autosomal dominant traits.

II. X-linked traits.

III. Y-linked traits.

IV. Pseudoautosomal inheritance.

Terms

Notes
(1) The term sex linkage has been used historically as equivalent to X-linkage, there having been no known functional genes on the Y chromosome. While X-linkage is the preferred term now, sex-linkage is still encountered in the meaning of X-linkage.
(2) Page 89, definition of hemizygous: This word is defined more generally than suggested here. It refers to any chromosome or chromosomal segment for which there is no homolog present.
(3) Page 107, Science and Society item 2: The pedigree of ichthyosis described has been proved to have been modified for purposes of show business. The correct version is inconsistent with Y linkage.

I. Transmission of autosomal dominant traits.

II. Transmission of X-linked genes.

III. Transmission of Y-linked genes (holandric inheritance)

IV. Pseudoautosomal inheritance.



Terms
dominant codominant brachydactyly
Marfan syndrome achondroplasia hypercholesterolemia
Huntington disease
X-linked
sex-linked
hemizygous
Y-linked
hemophilia
muscular dystrophy
holandric
pseudoautosomal

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last revision: 16 August 1999
owned by: Dr. Eldon Sutton