Zoo 317: Heredity, Evolution and Society

Fall 1999

Exam I from Fall 1998

These questions, administered in Fall 1998, covered the same material as the first exam to be given in Fall 1999. None of the questions is likely to appear on the 1999 exam. However, If you can answer all of them, you should do very well on the 1999 exam.

Reminder: Bring a photo ID to class. You will need it to turn in your exam.

Mark the correct answer on the separate answer sheet with a #2 pencil. On the answer sheet, be sure to (1) print your name, (2) code your name, (3) enter your SSN, (4) code your SSN, (5) sign with your usual signature. There is one best answer for each question. Other answers may be partially correct but not in all circumstances. If you must erase, do so thoroughly so that the machine will not misread your intentions. Answer sheets must be turned in no later than 9:50. You may keep the exam. The answer key will be posted outside the exam room about 9:25.

1. Eugenics and genetics differ in that

2. Which of the following groups contain only eukaryotes? 3. Which of the following organelles is especially important in generating energy for the cell? 4. Chromatin is found in 5. Ribosomes are the site of synthesis of 6. In humans, a haploid set of chromosomes consists of ________ chromosomes. 7. A telocentric chromosome is one in which the centromere is 8. Which is the proper sequence of periods of the cell (nuclear) cycle? 9. Mitosis is the form of cell replication that occurs in 10. Following mitosis, the two daughter cells 11. Metaphase is the point in the nuclear division cycle when 12. Preparation of a karyotype involves 13. Which of the following is an example of asexual reproduction? 14. Crossing over generates 15. The products of meiosis normally are 16. Meiosis is initiated in females 17. An ovum with one polar body 18. Which of the following is the proper sequence of stages in spermatogenesis? 19. A monohybrid cross is defined as 20. In leopards, presence of spots is dominant to absence (albino). The locus is autosomal. If a true-breeding spotted leopard is bred with an albino, what would be the expected phenotype of the F1 offspring? 21. In the above cross, what is the predicted genetic ratio of the F2 generation? [Let S represent the allele for spots and s the allele for albinism.] 22. At a second locus in leopards, long tail is dominant to short tail. Let the tail length alleles be represented by T (long) and t (short). The tail length and spotted loci segregate independently. If long tail, spotted leopards that are heterozygous at both loci are crossed with short tail, albino leopards, what would be the expected offspring? 23. A Punnett square is 24. A couple seeks genetic counseling because their second child has cystic fibrosis. What is the likelihood that their next child will have cystic fibrosis? 25. A genetic trait that is due to variation at an autosomal locus 26. One characteristic of rare autosomal recessive traits is 27. A wild-type allele is 28. Consanguineous matings are those that 29. A child is diagnosed with a rare autosomal dominant trait, such as brachydactyly. One would expect to find 30. A woman is diagnosed with the rare autosomal dominant trait Marfan syndrome. If she has a son, the likelihood that the child will also be affected is 31. One characteristic of X-linked dominant traits is 32. An X-linked recessive trait such as colorblindness appears much more frequently in males because 33. Which of the following would rule out X-linked recessive inheritance for a rare trait? 34. If a trait is Y-linked, 35. Traits are pseudoautosomal 36. Which cell organelles (other than the nucleus) have their own genes? 37. Which of the following is characteristic of maternal inheritance? 38. In the case of maternal inheritance, the genes involved will be identical in a woman and 39. An autosomal dominant allele is described as 90% penetrant. This means that 40. Occasionally a trait is due to genotype in some persons but to environmental factors in others. The latter are called 41. Two loci are 10 centimorgans apart on chromosome 5. This means that 42. Specific alleles at two loci are sometimes described as coupled. This means that 43. The term haplotype refers to 44. Mouse/human cell hybrids are useful in genetic mapping because 45. The gene for Duchenne muscular dystrophy (DMD) is syntenic with X-linked colorblindness. Therefore, 46. A locus that is polymorphic 47. The risk of nondisjunction is highest in which of the following paternal decades? 48. One feature of Down syndrome is the high risk associated with 49. Trisomy 21 is an example of 50. Embryos that are triploid most often arise by 51. Amniocentesis for prenatal diagnosis is best done at 52. When part of a chromosome is deleted, abnormality may result because 53. Some cases of Down syndrome are caused by an unbalanced 54. The XYY syndrome commonly arises by

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last revision: 15 September 1999
owned by: Dr. Eldon Sutton