Jennifer McKinney

jen

 

Graduate Research Assistant
Department of Pharmacology and Toxicology
University of Texas-Austin

 

Education:

2008 – M.S.  in Biochemistry Texas State University –San Marcos

2006 – B.S. in Biochemistry Texas State University – San Marcos

 

Research:

A.  Yeast screening to identify gene products involved in fragility, and characterization through mammalian cells to confirm phenotype. Determining mechanisms using cell lines and biochemistry.

B. ADAR1 (adenosine deaminase acting on RNA; adenosine to inosine in RNA, contains Z-DNA binding motif) effect on Z-DNA-inudced mutagenesis.
      Determining the effect of ADAR1 on mutation frequencies of Z-DNA versus H-DNA and control DNA.

 

Publications:

McKinney JS, Sethi S, Tripp JD, Nguyen TN, Sanderson BA, Westmoreland JW, Resnick MA, Lewis LK .A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae. BMC Genomics. 2013 Apr 15;14(1):251. doi: 10.1186/1471-2164-14-251.

 

Westmoreland JW, Summers JA, Holland CL, Resnick MA, Lewis LK. Blunt-ended DNA double-strand breaks induced by endonucleases PvuII and EcoRV are poor substrates for repair in Saccharomyces cerevisiae.DNA Repair (Amst). 2010 Jun 4;9(6):617-26. Epub 2010 Mar 30

 

Teaching Experience:

1.  Lecturer, Texas State University – San Marcos (2008 – 2009) - Organic Chemistry and Chemistry for Non-majors.
2.  Graduate Instructional Assistant, Texas State University – San Marcos (2007 – 2008) – General Chemistry, Organic Chemistry, Advanced Biochemistry, Quantitative Analysis.

 

Awards:

Dorothy Coker Fellowship Recipient (summer, 2007)

Outstanding Graduate Instructional Assistant Award (April, 2007)

 

Presentations:

2006 – Poster Presentation at ASBMB conference, Washington D.C.
“Multiple Pathways of Repair for Endonuclease-Induced Double-Strand
Breaks Within Chromosomal DNA"