Dr. Junhua Zhao PhD

Postdoctoral Fellow

junhua

Lab Video Producer

RESEARCH

2007-present- Postdoctoral Fellow,Vasquez Lab, The University of Texas at Austin

Investigated mechanism of recognizing and processing DNA interstrand crosslink induced by chemotherapeutic agent psoralen-TFO for cancer treatment. Discovered novel interaction between mismatch repair complex and nucleotide excision repair complexes on psoralen-induced DNA interstrand crosslink damage.

Comparing mechanisms of non-B DNA structure-induced genomic instability in bacteria, yeast and human cells. Completed construction of yeast shuttle vector and yeast artificial chromosome containing non-B DNA structure-forming sequences. Discovered the mutagenesis of non-B structure-forming sequences in yeast.

Characterizing mutations generated by non-B DNA structures in yeast genomic DNA. Screening gene products affecting mutagenicity of non-B structures genome-wide.

 

PUBLICATIONS

1. Zhao J, Jian A, Iyer RR, Modrich PL, Vasquez KM (2009) Nucl. Acid Res. In press.

2. Zhao J, Wang G, Bacolla A, Vasquez KM (2009) Cellular and Molecular Life Sciences. In press.

3. Wang G, Zhao J, Vasquez KM (2009) Methods.

4. Zhao J, Niu W, Yao J, Mohr S, Marcotte EM, Lambowitz AM (2008) PLoS Biology 6(6): e150.

5. Zhao J, Lambowitz AM (2005) Proc. Natl. Acad. Sci. USA 102:16133-40.

 

EDUCATION

2007- The University of Texas at Austin Ph.D. in Cellular and Molecular Biology

2000- The University of Science and Technology of China B.S. in Cellular and Molecular Biology,

 

 

 

ACADEMIC ACTIVITIES

Invited reviewer for the peer-reviewed journal ‘Molecular Carcinogenesis’.

Poster at the American Society for Microbiology (ASM) 108th General Meeting.

Platform presentation at the 36th Texas Genetics Society Annual Meeting.

 

TEACHING EXPERIENCE

Lecturer, University of Texas/M.D. Anderson Summer Undergraduate Research Program (2008-2009).

Graduate Teaching Assistant, University of Texas at Austin (Fall, 2006). Physiology and Human Anatomy Laboratory.

 

ASSOCIATION AND VOLUNTEERING SOCIETY MEMBERSHIP

AACR, EMS, LLS, American Cancer Society–RFL