The University of Texas at Austin

The George McMillan Fleming Center for Law and Innovation in Biomedicine and Healthcare

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Law and Innovation: the Embryonic Stem Cell Controversy
May 1–2, 2009

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The George McMillan Fleming Center for Law and Innovation in Biomedicine and Healthcare

Law and Innovation: the Embryonic Stem Cell Controversy

Law and Innovation: the Embryonic Stem Cell Controversy - Speakers

Andrea Bonnicksen
Northern Illinois University

Andrea Bonnicksen (PhD, Washington State University) is professor and former chair of the Department of Political Science at Northern Illinois University, where she teaches courses in biomedical and biotechnology policy. She is the author of three books, including Crafting a Cloning Policy: From Dolly to Stem Cells and In Vitro Fertilization: Building Policy from Laboratories to Legislatures. She is the coeditor of three books and the former book review editor for Politics and the Life Sciences. She has published journal articles and book chapters on ethical and policy issues related to embryonic stem cell research, human reproductive cloning, germ-line gene therapy, pre-implantation genetic diagnosis, ovum nuclear transfer, human embryo freezing, and other reproductive and genetic technologies.

Dan W. Brock
Harvard Medical School

Dan W. Brock is Frances Glessner Lee Professor of Medical Ethics and director of the Division of Medical Ethics at the Harvard Medical School, where he also directs the University Program in Ethics and Health. He received his BA in economics from Cornell University and his PhD in philosophy from Columbia University. He served as staff philosopher on the President’s Commission for the Study of Ethical Problems in Medicine in 1981–1982, was a member of the Ethics Working Group of the Clinton Task Force on National Health Reform in 1993, was president of the American Association of Bioethics in 1995–1996, and is an elected member of the Institute of Medicine. He is the author of over 150 published papers in bioethics and in moral and political philosophy, and of Deciding For Others: The Ethics of Surrogate Decision Making (with Allen E. Buchanan), Life and Death: Philosophical Essays in Biomedical Ethics, and From Chance to Choice: Genetics and Justice (with Allen Buchanan, Norman Daniels, and Daniel Wikler).

Ronald A. Carson
University of Texas Medical Branch at Galveston, Emeritus

Ronald A. Carson, PhD, is Harris L. Kempner Distinguished Professor Emeritus and former director of the Institute for the Medical Humanities at the University of Texas Medical Branch at Galveston. An adjunct faculty member in the University of Texas at Austin’s Plan II Honors Program, he is the editor of four books and author of numerous articles and chapters in both humanities and medical publications; an elected fellow of the Hastings Center; and former president of the Society for Health and Human Values, and a recipient of that society’s Annual Award.

Timothy Caulfield
University of Alberta

Timothy Caulfield has been research director of the Health Law Institute at the University of Alberta since 1993. In 2001 he received a Canada Research Chair in Health Law and Policy. He is also a professor in the Faculty of Law and the School of Public Health. He is a senior health scholar with the Alberta Heritage Foundation for Medical Research, the principal investigator for the Genome Canada project on the regulation of genomic technologies, the theme leader in the Stem Cell Network and the Advanced Foods and Materials Network (National Centres of Excellence) and has several projects funded by the Canadian Institutes of Health Research. He is a member of the Royal Society of Canada and the Canadian Academy of Health Sciences. He teaches biotechnology in the University of Alberta’s Faculty of Law and is the editor for the Health Law Journal and Health Law Review.

R. Alta Charo
University of Wisconsin Law School

R. Alta Charo is the Warren P. Knowles Professor of Law and Bioethics at the University of Wisconsin-Madison, where she is on the faculty of the Law School and the Medical School’s Department of Medical History and Bioethics. Charo offers courses on public health law, biotechnology law, food and drug law, bioethics, reproductive rights, and torts. She is an elected member of the National Academies Institute of Medicine, and served as a member of the Obama-Biden Transition Project, where she was a member of the Health and Human Services review team, focusing her attention particularly on transition issues related to the National Institutes of Health, the Food and Drug Administration, bioethics, stem cell policy, and women’s reproductive health.

Her work on stem cell policy includes service in 1994 on the NIH Human Embryo Research Panel; in 1996–2001 on President William Clinton’s National Bioethics Advisory Commission; in 2005 on the National Academies committee that drafted the first set of national stem cell research guidelines, as well as the California Institute for Regenerative Medicine working group on ethics standards; and from 2006 to the present as cochair of the National Academies’ Human Embryonic Stem Cell Research Advisory Committee.

Richard M. Doerflinger
U.S. Conference of Catholic Bishops

Richard M. Doerflinger is associate director of the Secretariat of Pro-Life Activities, United States Conference of Catholic Bishops, where he has worked for twenty-nine years. Among his duties is the preparation of policy statements and congressional testimony on abortion, euthanasia, embryo research, human cloning, and other medical-moral issues for the bishops’ conference. He is also adjunct fellow in bioethics and public policy at the National Catholic Bioethics Center in Philadelphia, and serves on the Advisory Board to the Center for Bioethics and Human Dignity in Bannockburn, Illinois.

He has testified before Congress, the National Bioethics Advisory Commission, the National Institutes of Health, the President’s Council on Bioethics, and several state legislatures on ethical issues involving human embryonic stem cell research and cloning. He has also spoken and published widely on these and other medical-moral issues, including contributions to Hastings Center Report, Duquesne Law Review, Cell Proliferation, the Kennedy Institute of Ethics Journal, the Encyclopedia of Catholic Doctrine, the National Catholic Bioethics Quarterly, and the American Journal of Bioethics. He has contributed a chapter to two books: Stem Cell Research: New Frontiers in Science and Ethics and Human Dignity in the Biotech Century. He holds a BA and an MA in divinity from the University of Chicago, and conducted doctoral studies in theology at that institution and the Catholic University of America.

Rebecca Dresser
Washington University

Rebecca Dresser is the Daniel Noyes Kirby Professor of Law and Professor of Ethics in Medicine at Washington University in St. Louis. Since 1983, she has taught medical and law students about legal and ethical issues in end-of-life care, biomedical research, genetics, assisted reproduction, and related topics. Before coming to Washington University, she taught at Baylor College of Medicine and Case Western Reserve University. In 2003, she was a visiting research scholar at the University of Tokyo, where she taught a short course in law and bioethics. Dresser received her law degree from Harvard Law School. She is a fellow of the Hastings Center and is one of the “At Law” columnists for the Hastings Center Report. Her book, When Science Offers Salvation: Patient Advocacy and Research Ethics, was published by Oxford University Press in 2001. She is a coauthor of The Human Use of Animals: Case Studies in Ethical Choice and Bioethics and Law: Cases, Materials and Problems. Dresser has written commissioned papers for the National Academy of Sciences and National Bioethics Advisory Commission. Since 2002, she has been a member of the President’s Council on Bioethics.

Norman Fost
University of Wisconsin-Madison

Norman Fost is professor of pediatrics and bioethics; vice chair of the Department of Medical History and Bioethics; director and founder of the Program in Medical Ethics; and works as a general pediatrician and as a member of the Child Protection Team at the University of Wisconsin-Madison, where he has taught since 1973. He is a graduate of Princeton (AB, 1960), Yale (MD, 1964), and Harvard (MPH, 1973). As chair of the University of Wisconsin-Madison Health Sciences Institutional Review Boards, Fost led the review and oversight process for Dr. James Thomson’s studies of human embryonic stem cells, beginning in 1995. He also chaired the university’s Bioethics Advisory Committee, which developed the first guidelines in the country for human embryonic stem cell research. He was a member of the American Association for the Advancement of Science Working Group on Stem Research, whose report was published in 1999; and a member of the National Academy of Sciences Committee on Guidelines for Human Embryonic Stem Cell Research, whose report was published in 2005.

From 1994 to 1998 he was an elected member of the Princeton University Board of Trustees. In 1997 he was awarded the Nellie Westermann Prize for Research Ethics and twice was runner-up. In 2003, he was awarded the William G. Bartholomew Award for Excellence in Ethics by the American Academy of Pediatrics. In 2006 he received a lifetime achievement award for his work in protection of human subjects in research, and in 2007 he was named the first winner of the Patricia Price Browne Award in bioethics.

John M. Golden
University of Texas School of Law

John M. Golden is an assistant professor at the University of Texas School of Law, where he teaches patent law and administrative law. He previously worked in the intellectual property department of Wilmer Cutler Pickering Hale and Dorr LLP in Boston. Before attending law school, he completed a PhD in physics at Harvard University. After law school, he clerked for the Honorable Michael Boudin of the United States Court of Appeals for the First Circuit, and for the Honorable Stephen Breyer of the United States Supreme Court.

Lawrence S. B. Goldstein
University of California, San Diego, School of Medicine

Lawrence S.B. Goldstein is a professor of cellular and molecular medicine at the University of California, San Diego, School of Medicine and director of the Stem Cell Program there. He is also an investigator with the Howard Hughes Medical Institute. He has been with the School of Medicine since 1993. He received his BA in biology and genetics from UCSD in 1976 and his PhD in genetics from the University of Washington, Seattle, in 1980. His research is focused on understanding the molecular mechanisms of movement inside brain cells and how failures in the movement systems may lead to neurodegenerative diseases. His laboratory has discovered important links between transport processes and diseases such as Alzheimer’s and Huntington’s diseases.

He has had an active role in national science policy, having served on many public scientific advisory committees, in addition to serving as an expert commentator on the issue of stem cell research and biomedical research policy by print and broadcast media. He has testified on a number of occasions in the U.S. House of Representatives and the Senate about NIH funding and stem cell research. Goldstein also served as cochair of the scientific advisory committee to the campaign for the Proposition 71 stem cell research initiative, which authorizes $3 billion in tax-free state bonds to fund stem cell research in California over ten years. As a cofounder and consultant for the biotechnology company Cytokinetics, he has also had an active role in private industry, where he has gained experience in translating scientific insights to new therapeutic approaches.

Ronald M. Green
Dartmouth College

A member of Dartmouth’s Religion Department since 1969, Ronald Green also serves as the faculty director of Dartmouth’s Ethics Institute, a consortium of faculty concerned with teaching and research in applied and professional ethics. He is a summa cum laude graduate of Brown University and received his PhD in religious ethics from Harvard University in 1973. In 1996 and 1997, Green served as director of the Office of Genome Ethics at the National Human Genome Research Institute of the National Institutes of Health. His research interests are in genetic ethics, biomedical ethics, and issues of justice in health care allocation. He is the author of six books and over 130 articles in theoretical and applied ethics. His most recent book, The Human Embryo Research Debates: Bioethics in the Vortex of Controversy, was published in 2001 by Oxford University Press. In 2005, Green was named a Guggenheim Fellow.

He serves on the bioethics committee of the March of Dimes. In 1994 he was a member of the Human Embryo Research Panel of the NIH, a blue-ribbon commission appointed to recommend policy for federal funding of research on the pre-implantation human embryo. In 1998–1999, Green was president of the Society of Christian Ethics. He served two elected terms as secretary of the American Academy of Religion, the largest professional association of religious studies educators in the United States. He currently heads the Ethics Advisory Board of Advanced Cell Technology, a company involved in therapeutic cloning research. In 1980 he received the Dartmouth Distinguished Teaching Award. This award, given to a single member of the faculty annually, is voted upon by the entire graduating class.

Insoo Hyun
Case Western Reserve University School of Medicine

Insoo Hyun is associate professor in the Department of Bioethics at Case Western Reserve University School of Medicine. He received his PhD in philosophy from Brown University and his BA and MA in philosophy from Stanford. In 2005, he was awarded a Fulbright Research Award by the U.S. Department of State to study the ethical, legal, and cultural dynamics of human research cloning in South Korea. In 2006 he chaired the Subcommittee on Human Biological Materials Procurement for the International Embryonic Stem Cell Guidelines Task Force, a multinational, multidisciplinary working group for the International Society for Stem Cell Research. Currently, Hyun is chair of the ISSCR’s Ethics and Public Policy Committee and cochair of the ISSCR Task Force on International Guidelines for the Clinical Translation of Stem Cells. Hyun’s bioethics articles have appeared in Science, Nature, Cell Stem Cell, the Hastings Center Report, and the Kennedy Institute of Ethics Journal, among others.

Bernard Lo
University of California, San Francisco

Bernard Lo, MD, is professor of medicine and director of the Program in Medical Ethics at the University of California, San Francisco. He is national program director for the Greenwall Faculty Scholars Program in Bioethics. He is cochair of the Standards Working Group of the California Institute of Regenerative Medicine, which recommends regulations for stem cell research funded by the state of California. He also serves on the Data and Safety Monitoring Committees for diabetes prevention trials and an HIV vaccine trial at the National Institute of Allergy and Infectious Diseases.

He is a member of the Ethics Working Group of the NIH-sponsored HIV Prevention Trials Network, which carries out clinical trials in developing countries. He is codirector of the Policy and Ethics Core of the Center for AIDS Prevention Studies at UCSF, which provides technical advice and consultation to researchers carrying out clinical research, including research in resource-poor nations. He is a member of the Institute of Medicine (IOM) and serves on the IOM Council.

He has been involved in a number of studies on ethical issues in human participants research carried out by the IOM and the National Academy of Sciences. He formerly chaired a IOM panel on confidentiality in health services research. He developed a course on the responsible conduct of research that one hundred postdoctoral fellows and junior faculty take each year. He and his group also carry out research on ethical issues in human participants research, end-of-life decisions, and stem cell research.

David Magnus
Stanford University

David Magnus, PhD, is associate professor of pediatrics and medicine at Stanford University, where he is director of the Stanford Center for Biomedical Ethics and cochair of the Ethics Committee for the Stanford Hospital. He received his PhD in philosophy from Stanford University and has published articles on a range of topics in bioethics, particularly on issues concerning genetic technology, cloning, and stem cell research. He currently serves on the California Human Stem Cell Research Advisory Committee. He is the principle editor of a collection of essays, Who Owns Life?, and his publications have appeared in Science, Nature Biotechnology, and the British Medical Journal. He serves as associate editor of the American Journal of Bioethics. He has appeared on many television shows, including Good Morning America, CBS This Morning, FOX News Sunday, and ABC World News, several nationally syndicated radio shows, and has been quoted in Time, Newsweek, the Wall Street Journal, the New York Times, and USA Today, among other publications. In addition to his scholarly work, he has published a number of editorial pieces in prominent newspapers.

John A. Robertson
University of Texas School of Law

John A. Robertson holds the Vinson and Elkins Chair at the University of Texas School of Law. He has written and lectured widely on law and bioethical issues. He is the author of two books in bioethics, The Rights of the Critically Ill and Children of Choice: Freedom and the New Reproductive Technologies, and numerous articles on reproductive rights, genetics, organ transplantation, and human experimentation. He has served on or been a consultant to many national bioethics advisory bodies, and is currently chair of the Ethics Committee of the American Society for Reproductive Medicine.

William M. Sage
University of Texas

William M. Sage, Vice Provost for Health Affairs at the University of Texas, earned his AB at Harvard in 1982 and his MD and JD from Stanford in 1988. He served as a resident in anesthesiology and critical care medicine at the Johns Hopkins Hospital in 1989–1990 and as an associate at O’Melveny & Myers in Los Angeles in 1990–1995. He has also served on the President’s Task Force on Health Care Reform, in 1993, and was an elected fellow at the Hastings Center and taught at Columbia Law School in 1995–2006. His current areas of teaching are health law, regulatory theory, antitrust, and professional responsibility. He was principal investigator for the Pew Charitable Trusts Project on Medical Liability in Pennsylvania from 2002 to 2005 and received the Robert Wood Johnson Foundation Investigator Award in Health Policy Research in 1998. He is on the editorial board of Health Affairs and served on the Institute of Medicine’s Committee on Rapid Advances in Health Care in 2002. He has also served on the JCAHO Tort Resolution and Injury Prevention Roundtable, in 2004–2005. Sage is the coeditor of Medical Malpractice and the U.S. Health Care System, Uncertain Times: Kenneth Arrow and the Changing Economics of Health Care, and numerous articles.

Lawrence Sager
University of Texas School of Law

Lawrence Sager is one of the nation’s preeminent constitutional theorists and scholars, and Dean of the University of Texas School of Law. Sager came to Texas from New York University School of Law, where he was the Robert B. McKay Professor and cofounder of the Program in Law, philosophy, and Social Theory. He has also taught at Harvard, Princeton, Boston University, UCLA, and the University of Michigan. Dean Sager is the author or coauthor of dozens of articles, many now classics in the canon of legal scholarship. Sager is the author of two books: Justice in Plainclothes: A Theory of American Constitutional Practice and Religious Freedom and the Constitution (coauthored with Christopher Eisgruber).

Margaret Sampson
Vinson & Elkins LLP

Margaret Sampson’s principal areas of practice are global strategic patent counseling and patent litigation primarily in the areas of pharmaceuticals, biotechnology, research tools, and medical devices. Sampson has experience advising clients in areas such as Hatch-Waxman patent litigation, drug delivery systems, and genetic engineering. Her scientific experience is in molecular genetics, recombinant DNA, and stem cell research, in which she studied the role of voltage dependent anion channels in energy metabolism by generating targeted mutations in mice.

Christopher Thomas Scott
Stanford University

Christopher Thomas Scott is director of the Stanford University Program on Stem Cells in Society, a senior research scholar in the Center for Biomedical Ethics, and an associate fellow at King’s College, London. His research interests focus on the social, economic, political, and ethical dimensions of regenerative medicine. His recent book, Stem Cell Now: An Introduction to the Coming Medical Revolution, has been translated into four languages. Scott was the former assistant vice chancellor at the University of California, San Francisco. He is a cofounder and CEO of The Stem Cell Advisors, Inc., a California public-benefit nonprofit providing stem cell research review and oversight for biotechnology companies and research institutions. Scott is an ethics and policy committee member for the International Society of Stem Cell Research, and a member of the Center for Biomedical Ethics, and a board member of the Institute for Stem Cell Biology in Zurich.

Paul J. Simmons
Center for Stem Cell Research at the Brown Foundation of Molecular Medicine

Paul J. Simmons serves as professor and director of the Center for Stem Cell Research at the Brown Foundation Institute of Molecular Medicine at University of Texas Health Sciences Center in Houston. He is also president of the International Society for Stem Cell Research. Simmons graduated from Queen Elizabeth College, University of London, with a BS in cell biology. In 1985 he received his PhD from the University of Manchester, where his research focused on understanding the nature of the stromal cell microenvironment responsible for regulating the growth and differentiation of hematopoietic cells in long-term bone marrow cultures. He carried out postdoctoral research at the BC Cancer Research Centre in Vancouver, British Columbia, and in the Department of Transplantation Biology at the Fred Hutchinson Cancer Research Center in Seattle, Washington.

He was the inaugural R.L. Clifford Fellow in Experimental Haematology at the Hanson Centre for Cancer Research in Adelaide, Australia, where he served as chief hospital scientist from 1995 to 1999. In 1999 he was appointed program head in stem cell biology at the Peter MacCallum Cancer Centre in Melbourne, Australia, and served there until his appointment in 2006 to the Brown Foundation in Houston. Simmons is or has served as associate editor for Experimental Hematology, Cytotherapy, and Stem Cell Research, and is on the editorial boards of Cell, Stem Cell, and Blood and Stem Cells. The major focus of Simmons’s research has been to use the paradigm of the hematopoietic system as a model to understand the mechanisms that contribute to the extrinsic regulation of stem cells in adult organs by the tissue microenvironment (stem cell niche) in which the stem cells reside.

Bonnie Steinbock
University at Albany-SUNY

Bonnie Steinbock received her PhD in philosophy from the University of California, Berkeley. She is a faculty member of the Alden March Bioethics Institute at Albany Medical College and the Union Graduate College-Mount Sinai School of Medicine Bioethics program. A fellow of the Hastings Center, and the chair of its Fellows Council, she is also a member of the Ethics Committee of the American Society for Reproduction and Medicine. Her recent articles have been on the moral status of embryos, embryonic stem cell research, prenatal genetic testing, and reproductive cloning. She is the author of Life Before Birth: The Moral and Legal Status of Embryos and Fetuses and the editor of Legal and Ethical Issues in Human Reproduction and The Oxford Handbook of Bioethics. She is a coeditor (with John Arras and Alex John London) of the seventh edition of Ethical Issues in Modern Medicine; Killing and Letting Die (with Alastair Norcross); New Ethics for the Public’s Health (with Dan Beauchamp); and Public Health Ethics: Theory, Policy and Practice (with Ronald Bayer, Larry Gostin, and Bruce Jennings).

Robert Streiffer
University of Wisconsin-Madison

Robert Streiffer’s research includes bioethics, ethical theory, metaethics, and political philosophy, with a focus on ethical and policy issues arising from modern biotechnology. He is currently working in two areas. The first is on ethical and policy issues arising from the creation of chimeras, organisms with parts from different species, through the xenotransplantation of human stem cells into animals that are in the embryonic or early fetal stages of development. The second is on ethical and policy issues arising from the application of biotechnology to animals in agriculture. He has served on the Health Sciences Institute Review Board and is presently serving on the university’s Hospital Ethics Committee, Biotechnology Advisory Committee, and Stem Cell Research Oversight Committee. He received his PhD in ethics from the Massachusetts Institute of Technology in 1999 and is a tenured associate professor at the University of Wisconsin-Madison.

Jeremy Sugarman
Johns Hopkins University

Jeremy Sugarman, MD, MPH, MA, is the Harvey M. Meyerhoff Professor of Bioethics and Medicine, professor of medicine, professor of health policy and management, and deputy director for medicine of the Berman Institute of Bioethics at the Johns Hopkins University. He conducts both theoretical and empirical research in medical ethics. His work concentrates on informed consent, research ethics, and the ethical issues associated with emerging technologies. He is the author of over 175 publications in peer-reviewed journals. He has also edited or coedited four books: Beyond Consent: Seeking Justice in Research; Ethics of Research with Human Subjects: Selected Policies and Resources; Ethics in Primary Care; and Methods in Medical Ethics. Sugarman is an associate editor of Clinical Trials, a contributing editor for IRB, and is on the editorial boards of Accountability in Research and Theoretical Medicine and Bioethics. He serves on the Scientific and Research Advisory Board for the Canadian Blood Service and is a member of the Maryland Stem Cell Research Commission. He is currently chair for the Ethics Working Group of the HIV Prevention Trials Network, the ethics officer for the Resuscitation Outcomes Consortium, and cochair of the Johns Hopkins Embryonic Stem Cell Research Oversight Committee. He is also a member of the American Society of Clinical Investigation and a fellow of the American Association for the Advancement of Science, the American College of Physicians, and the Hastings Center.

Patrick L. Taylor
Children’s Hospital Boston

Patrick L. Taylor is deputy general counsel and chief counsel, research affairs, at Children’s Hospital Boston, in a position focused mostly on legal and policy issues in biomedical research, biotechnology (including intellectual property, start-ups and licensing), research ethics, privacy, human subject protection, and compliance. He has had a diverse career in representing and counseling not-for-profit, for-profit, and government clients involved in health, biotechnology, medical research, and human services. He started his career on Wall Street, and later moved into roles in New York City government as an appellate lawyer working on issues of homelessness and child poverty. He then joined New York State government, first as assistant counsel for health and human services to New York Governor Mario M. Cuomo, and later as chief of staff for education and senior counsel to the majority for the New York State Assembly. Before coming to Children’s Hospital he was senior vice president and general counsel for Albany Medical Center in New York, and held various local faculty positions teaching health law and policy.

He received his BA with honors from the University of Wisconsin-Madison (Phi Beta Kappa), and received his JD with academic honors from Columbia University Law School. He also holds a faculty position as an assistant clinical professor at Harvard Medical School, is a past fellow in medical ethics at Harvard, and is on the Advisory Board of the Science and Technology Studies Program of the Kennedy School of Government at Harvard University. His research and writing focus on issues in research ethics, academic-industry collaborations, conflicts of interest, stem cell research, science policy, privacy, genomics and genetics, and the electronic medical record network. His writings have appeared in Nature, Science, Nature Biotechnology, Cell Stem Cell, Academic Medicine, Drug Development, and Science and Engineering Ethics, among others, as well as various legal journals, including the health law journals of the American Bar Association and the New York State Bar Association.