University of Texas - College of Pharmacy - CMCT

Center for Molecular & Cellular Toxicology

CMCT Faculty

CRITICAL DEVELOPMENTAL PERIODS & ENDOCRINE/HORMONE DISRUPTION

C. Marcelo Aldaz, M.D., Professor, UT MD Anderson Cancer Center, Science Park-Research Division; Breast cancer, hormonal carcinogenesis; Mammary tumor models.
http://sciencepark.mdanderson.org/Documents/CAldaz/Aldaz.html

David Crews, Ph.D., Professor of Integrative Biology; How biological and chemical factors early in development influence the development of behavior and its neural substrates of various vertebrate species, particularly the development and function of sex and individual differences. http://www.biosci.utexas.edu/directory/details.aspx?id=1506

Richard H. Finnell, Ph.D., Professor, Department of Nutritional Sciences and Director of Genomic Research at the Dell Children’s Medical Center; Study of the interaction between specific genes and nutritional factors as they influence normal embryonic development; revealing the relationships between the folic acid metabolic pathway and risk genes associated with birth defects.
http://finnelllab.com

Andrea C. Gore, Ph.D., Professor of Pharmacology and Toxicology; Neural mechanisms of reproductive development and puberty, Effects of environmental and hormonal factors that perturb reproductive function, Neural mechanisms for reproductive senescence.
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/gore.html

John H. Richburg, Ph.D., Professor of Pharmacology and Toxicology; Mechanisms Regulating Apoptosis/Male Reproductive Toxicology. Peripubertal sensitivity to testicular toxicants.
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/richburg.html

Peter Thomas, Ph.D., Professor of Zoology and Marine Science; Reproductive endocrine toxicology, mechanisms of endocrine disruption by xenobiotic chemicals, environmental toxicology of aquatic organisms.
http://www.utmsi.utexas.edu/staff/thomas.htm

Carla Van Den Berg, PharmD., Associate Professor of Pharmacology and Toxicology; Role of growth factor-mediated treatment resistance in breast cancer.
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/vandenberg.html

MECHANISMS OF ENVIRONMENTAL CARCINOGENESIS

Mark T. Bedford, Ph.D., Professor, UT MD Anderson Cancer Center, Science Park-Research Division; Arginine methylation, WW domains, Protein-protein interactions, Gene targeting.
http://sciencepark.mdanderson.org/faculty/bedford_m/index.html

Shawn B. Bratton, Ph.D., Associate Professor, UT MD Anderson Cancer Center, Science Park-Research Division; Basic mechanisms of apoptosis.
http://www.mdanderson.org/education-and-research/departments-programs-and-labs/labs/bratton-lab/index.html

Kevin Dalby, Ph.D., Professor of Medicinal Chemistry; Potential for cancer treatment through the targeting of protein kinases by utilizing novel efforts in chemical biology.
http://www.utexas.edu/pharmacy/divisions/medicinalchem/faculty/dalby.html

John DiGiovanni, Ph.D., Professor of Pharmacology & Toxicology and Coulter R. Sublett Chair, Identification of critical targets for both the initiation and promotion stages of carcinogenesis.
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/digiovanni.html

Walter Fast, Ph.D., Associate Professor of Medicinal Chemistry; Enzymology of Arginine Modification and Bacterial Communication. Enzyme Mechanisms, Inhibitor Design, Protein Engineering.
http://www.utexas.edu/pharmacy/divisions/medicinalchem/faculty/fast.html

David G. Johnson, Ph.D., Professor, UT MD Anderson Cancer Center, Science Park-Research Division; E2F transcription factors, cell cycle, tumor suppressor genes, oncogenes.
http://sciencepark.mdanderson.org/Documents/DJohnson/johnson.html

Sean M. Kerwin, Ph.D., Associate Professor of Medicinal Chemistry; Covalent modification of DNA by small molecules including carcinogens, natural products, and drugs; G-quadruplex DNA structures as sites for DNA damage and drug interaction; synthesis of natural products and analogs to probe molecular mechanisms related to cancer prevention and treatment.
http://www.utexas.edu/pharmacy/divisions/medicinalchem/faculty/kerwin.html

Dean Tang, M.D., Ph.D., Professor of Carcinogenesis; Cancer stem cells, prostate cancer, and apoptosis.
http://sciencepark.mdanderson.org/labs/tang

Karen M. Vasquez, Ph.D., Professor of Pharmacology & Toxicology and Coulter R. Sublett Fellow; Elucidate the molecular mechanisms of DNA damage recognition by DNA repair and recombination pathways, Develop triplex technology to modify mammalian gene structure and function, Study the role of DNA structure in genomic instability and mutagenesis.
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/vasquez.html

Casey W. Wright, Ph.D., Assistant Professor of Pharmacology and Toxicology; Mechanisms of NF-kB signaling in lymphoid malignancies including how environmental sensors (AHR, ARNT) module NF-kB activity. http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/wright.html

DIET, ENERGY BALANCE AND ENVIRONMENTAL DISEASE RISK

Susan M. Fischer, Ph.D., Professor of Molecular Carcinogenesis, The University of Texas, M. D. Anderson Cancer Center-Science Park, Multistage chemical carcinogenesis, elucidate the function and regulation of the enzymes involved in arachidonic acid metabolism in skin, and develop dietary and other approaches to skin cancer prevention.
http://faculty.mdanderson.org/Susan_Fischer/

Stephen D. Hursting, Ph.D., Professor of Nutrition; Diet-gene interactions relevant to cancer prevention, particularly the molecular and hormonal mechanisms underlying energy balance-cancer associations.http://he.utexas.edu/directory/hursting-stephen

Kimberly Kline, Ph.D., Professor of Nutritional Sciences; Nutrition and cancer biology. http://he.utexas.edu/directory/kline-kimberly

Edward Mills, Ph.D., Associate Professor of Pharmacology and Toxicology; Understanding how mitochondria talk to other cellular components and how mitochondria participate in the pharmacologic and toxic actions of chemicals and in disease processes.
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/mills.html

Bob Sanders, Ph.D., Professor of Molecular Genetics and Microbiology; Cancer biology and immunology. http://he.utexas.edu/directory/sanders-bob-g

OTHER PARTICIPATING FACULTY

Richard L. Corsi, Ph.D., Professor, Department of Civil, Architectural and Environmental Engineering;Analysis and control of fugitive contaminant emissions from industrial wastewater and process streams; cross-media contaminant transport; atmospheric transport modeling; indoor air quality.
http://www.ce.utexas.edu/faculty-directory/profiles/richard-corsi.html

Last Reviewed: May 14, 2013

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