Recent Publications

 

Miller, D. J.; Ravikumar, K .S.; Shen, H.; Suh, J.-K.; Kerwin, S. M.; Robertus, J. "Structure-Based Design and Characterization of Novel Platforms for Ricin and Shiga Toxin Inhibition" J. Med. Chem. 2002, 45, 90–98.

Tuntiwechapikul, W.; David, W. M.; Kumar, D.; Salazar, M.; Kerwin, S. M. "DNA Modification by 4-Aza-3-ene-1,6-diynes: DNA Cleavage, pH-Dependent Cytosine-Specific Interactions, and Cancer Cell Cytotoxicity" Biochemistry 2002, 41, 5283-5290.

David, W. M.; Brodbelt, J.; Kerwin, S. M.; Thomas, P. W. “Investigation of Quadruplex Oligonucleotide-Drug Interactions by Electrospray Ionization-Mass Spectrometry” Anal. Chem. 2002, 74, 2029-2033.

Kumar, D., Jacob, M.; Reynolds, M.; Kerwin, S. M. “Synthesis and Evaluation of Anticancer Benzoxazoles and Benzimidazoles related to UK-1” Bioorg. Med. Chem., 2002, 10, 3997-4004.

Kern, J. T.; Thomas, P. W.; Kerwin, S. M. “The Relationship between Ligand Aggregation and G-quadruplex DNA Selectivity in a Series of 3,4,9,10-Perylenetetracarboxylic Acid Diimides” Biochemistry, 2002, 41, 11379-11389.

Feng, L., Kumar, D.; Kerwin, S. M. “An Extremely Facile Aza-Bergman Rearrangement of Sterically Unencumbered Acyclic 3-Aza-3-ene-1,5-diynes.” J. Org. Chem., 2003, 68, 2234-2242.

Feng, L.; Kerwin, S. M. “Isolation of a Cyclopropane-Containing Product from the Rearrangement of a 3-Aza-3-ene-1,5-diyne under Acid Catalysis” Tetrahedron Lett., 2003, 44, 3463–3466.

Feng, L.; Kumar, D.; Birney, D.; Kerwin, S. M. “,5-Didehydro-3-picoline Diradicals from Skipped Aza-Enediynes: Computational and Trapping Studies of an Aza-Myers-Saito Cyclization” Org. Lett., 2004, 6, 2059–2062.

Nadipuram, A.; Kerwin, S. M. “5H-Cyclopentapyrazines from 1,2-Dialkynylimidazoles” Synlett, 2004, 1404–1408.

Pothukuchy, A.; Mazzitelli, C.; Rodriguez, M. L.; Tuesuwan, B.; Salazar, M.; Brodbelt, J. S.; Kerwin, S. M. “Duplex and Quadruplex DNA binding and Photocleavage by Trioxatriangulenium Ion” Biochemistry 2005, 44, 2163 - 2172