Medicinal Chemistry

Faculty

Photo

Lee, Seongmin, Ph.D.
Associate Professor of Med. Chem.
PHR 3.206A
512-471-1785
SeongminLee@mail.utexas.edu


Selected Publications
  1. Structure of Escherichia coli 3-Methyladenine DNA Glycosylase AlkA Bound to Undamaged DNA. Bowman, B. R.; Lee, S.; Wang, S.; Verdine, G. L. 2010, J. Biol. Chem. 285, 35783-791

  2. Atomic Substitution Reveals the Structural Basis for Substrate Adenine Recognition and Removal by Adenine DNA Glycosylase.
    Lee, S.; Verdine, G. L. 2009, Proc. Natl. Acad. Sci. USA 106, 18497.

  3. Synthesis of C14,15-Dihydro-25-epi North Unit of Cephalostatin 1 via Redox Modifications of Hecogenin Acetate.
    Lee, S.; Jamieson, D.; Fuchs, P. L. Org. Lett. 2009, 11, 5.

  4. Chemistry of Trisdecacyclic Pyrazine Antineoplastics: The Cephalostatins and Ritterazines.
    Lee, S.; LaCour, T. G.; Fuchs, P. L. Chem. Rev. 2009, 109, 2275.

  5. Synthesis and Structure of Duplex DNA Containing the Genotoxic Nucleobase Lesion N7-Methylguanine.
    Lee, S.; Bowman, R. B.; Ueno, Y.; Verdine, G. L. J. Am. Chem. Soc. 2008, 130, 11570.


  6. Trapping and Structural Elucidation of a Very Advanced Intermediate in the Lesion-extrusion Pathway of hOGG1. (highlighted in Nat. Chem. Biol. 2008, 4,395)
    Lee, S.; Radom, C. T. Verdine, G. L. J. Am. Chem. Soc. 2008, 130, 7784.

  7. Structure of the Escherichia coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A  System for the Facile Structure Determination of Lesion-Containing DNA (Featured Article)
    Bowman, B. R*.; Lee, S.* (*equal authorship); Wang, S.; Verdine, G. L. Structure 2008, 16, 1166.


  8. A Concise Synthesis of 4′-F Nucleic Acids.
    Lee, S.
    ; Utammapinat, C.; Verdine, G. L. Org. Lett. 2007, 9, 5007.

  9. Catalytic Oxidation of C-H Bonds.
  10. Lee, S.; Fuchs, P. L. US Patent 7,196,192 (2007)

More information about Dr. Lee
> Lee Lab (Personal Pages)
> Return to Lee's Home Page
Last Reviewed: March 2, 2011

Division Information

Mailing Address:
The University of Texas
at Austin
Medicinal Chemistry
BME 6.202
College of Pharmacy
1 University Station,
C0850
Austin, TX
78712-0120
USA

Email Address: pharmacy
@www.utexas.edu

Phone:


Liu Honored with Scott Medal

Liu Photo
Dr. Hung-wen (Ben) Liu, professor of medicinal chemistry, has received the A.I. Scott Medal from Texas A&M University. The award recognizes excellence in biological chemistry research and was presented at an October gathering at College Station.
>Read more about this story.

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