Medicinal Chemistry

Faculty

Photo

Lee, Seongmin, Ph.D.
Assistant Professor of Med. Chem.
PHR 3.206A
512-471-1785
seongminlee123@gmail.com


Selected Publications
  1. Structure of Escherichia coli 3-Methyladenine DNA Glycosylase AlkA Bound to Undamaged DNA. Bowman, B. R.; Lee, S.; Wang, S.; Verdine, G. L. 2010, J. Biol. Chem. 285, 35783-791

  2. Atomic Substitution Reveals the Structural Basis for Substrate Adenine Recognition and Removal by Adenine DNA Glycosylase.
    Lee, S.; Verdine, G. L. 2009, Proc. Natl. Acad. Sci. USA 106, 18497.

  3. Synthesis of C14,15-Dihydro-25-epi North Unit of Cephalostatin 1 via Redox Modifications of Hecogenin Acetate.
    Lee, S.; Jamieson, D.; Fuchs, P. L. Org. Lett. 2009, 11, 5.

  4. Chemistry of Trisdecacyclic Pyrazine Antineoplastics: The Cephalostatins and Ritterazines.
    Lee, S.; LaCour, T. G.; Fuchs, P. L. Chem. Rev. 2009, 109, 2275.

  5. Synthesis and Structure of Duplex DNA Containing the Genotoxic Nucleobase Lesion N7-Methylguanine.
    Lee, S.; Bowman, R. B.; Ueno, Y.; Verdine, G. L. J. Am. Chem. Soc. 2008, 130, 11570.


  6. Trapping and Structural Elucidation of a Very Advanced Intermediate in the Lesion-extrusion Pathway of hOGG1. (highlighted in Nat. Chem. Biol. 2008, 4,395)
    Lee, S.; Radom, C. T. Verdine, G. L. J. Am. Chem. Soc. 2008, 130, 7784.

  7. Structure of the Escherichia coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A  System for the Facile Structure Determination of Lesion-Containing DNA (Featured Article)
    Bowman, B. R*.; Lee, S.* (*equal authorship); Wang, S.; Verdine, G. L. Structure 2008, 16, 1166.


  8. A Concise Synthesis of 4′-F Nucleic Acids.
    Lee, S.
    ; Utammapinat, C.; Verdine, G. L. Org. Lett. 2007, 9, 5007.

  9. Catalytic Oxidation of C-H Bonds.
  10. Lee, S.; Fuchs, P. L. US Patent 7,196,192 (2007)

More information about Dr. Lee
> Lee Lab (Personal Pages)
> Return to Lee's Home Page
Last Reviewed: March 2, 2011

Division Information

Mailing Address:
The University of Texas
at Austin
Medicinal Chemistry
BME 6.202
College of Pharmacy
The University of Texas
at Austin
2409 University Ave.
Stop A1900
Austin, TX, USA
78712-1113

Email Address: pharmacy
@www.utexas.edu

Phone:


Davis Awarded for Teaching Excellence

Davis
Dr. Patrick Davis, senior associate dean and professor of medicinal chemistry, is one of five University of Texas at Austin faculty members cited to receive a President's Associates Teaching Excellence Award.
>Read more about this award.

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