Whitman, Christian P., Ph.D.
Division Head,
Jacques P. Servier
Regents Professor
BME 6.202A
512-471-6198
whitman@mail.utexas.edu

de Jong, R.M., Bazzacco, P., Poelarends, G.J., Johnson, Jr., W.H., Kim, Y.-J., Burks, E.A., Serrano, H., Thunnissen, A.-M.W.H., Whitman, C.P., Dijkstra, B.W. "Crystal Structures of Native and Inactivated cis-3-Chloroacrylic Acid Dehalogenase: Structural Basis for Substrate Specificity and Inactivation by (R)-Oxriane-2-carboxylate", J. Biol. Chem. 282, 2440-2449 (2007).
 
Gunsch, C.K., Kinney, K.A., Szaniszlo, P.J., Whitman, C.P. "Relative Gene Expression Quantification in a Fungal Gas-Phase Biofilter", Biotechnol. Bioeng. 98, 101-111 (2007).

Poelarends, G.J., Serrano, H., Johnson, Jr., W.H., and Whitman, C.P "The Phenylpyruvate Tautomerase Activity of trans-3-Chloroacrylic Acid Dehalogenase: Evidence for an Enol Intermediate in the Dehalogenase Reaction?",  Biochemistry 46, 9596-9604 (2007).

Wang, S.C, Johnson, Jr., W.H., Czerwinski, R.M., Stamps, S.L., and Whitman, C.P. "Kinetic and Stereochemical Analysis of YwhB, a 4-Oxalocrotonate Tautomerase Homologue in Bacillus subtilis:  Mechanistic Implications for the YwhB- and 4-Oxalocrotonate Tautomerase-catalyzed Reactions", Biochemistry, 46, 11919-11929 (2007).

White, T.A, Johnson, Jr., W.H., Whitman, C.P., and Tanner, J.J. "Structural Basis for the Inactivation of Thermus thermophilus Proline Dehydrogenase by N-Propargylglycine", Biochemistry, 47, 5573-5580 (2008)

Poelarends, G.J., Serrano, H., Person, M.D., Johnson, Jr., W.H., and Whitman, C.P. "Characterization of Cg10062 from Corynebacterium glutamicum:  Implications for the Evolution of cis-3-Chloroacrylic Acid Dehalogenase Activity in the Tautomerase Superfamily", Biochemistry 47, 8139-8147 (2008).

Robertson, B.A., Johnson, Jr., W.H., Lo, S. H.-H., and Whitman, C.P. "Inactivation of Cg10062, a cis-3-Chloroacrylic Acid Dehalogenase Homologue in Corynebacterium glutamicum,by (R)- and (S)-Oxirane-2-carboxylate:  Analysis and Implications", Biochemistry 47, 8796-8803 (2008)

Poelarends, G.J. and Whitman, C.P. "The Chemical Versatility of the b-a-b Fold:  Catalytic Promiscuity and Divergent Evolution in the Tautomerase Superfamily", Cell. Mol. Life Sci. 65, 3606-3618 (2008).

Pegan, S.D., Serrano, H., Whitman, C.P., and Mesecar, A.D., "Structural and Mechanistic Analysis of trans-3-Chloroacrylic Acid Dehalogenase Activity", Acta Crystallogr. D Biol. Crystallogr. 64, 1277-1282 (2008).