University of Texas - College of Pharmacy - Pharmaceutics

Pharmaceutics

Faculty

	Croyle, Maria A., Ph.D. Associate Professor PHR 4.214D 512-471-1972 macroyle@mail.utexas.edu
News Ebola Cards	July 24, 2009 Croyle Welcomes 40 Outstanding High School Seniors to Visit Virus Laboratory Twenty students fill a small lecture room chatting about what they have discovered while visiting the UT Austin campus. In rushes Dr. Maria Croyle, unbeknownst to them, with the announcement that something serious has happened in their small village here within this room and one person has fallen ill. While doing this she hands a somewhat shocked student a small card with a picture of the Ebola virus on it. She goes on to say that this individual rushes to her friends for help and in turn infects one of them (another student is given an Ebola card). Before they know it, 90% of the students in the room are holding Ebola cards. The exercise ends with approximately 75% of those infected holding "death" cards. This was one of several exercises used to illustrate how lethal pathogens spread and affect small isolated populations. Croyle then talked to the students about how these infections impact the state of Texas and the United States with respect to public health and economic policies. The class then toured her laboratory and got to witness how her group produces a recombinant vaccine against the Ebola virus from infecting cells used to grow the virus to final purification steps. The Honors Colloquium is an annual event during which The University of Texas at Austin opens it's doors to high school seniors primarily from Texas high schools that will eventually be named National Merit, National Achievement, or National Hispanic Finalists and Scholars, and compete for the university's honor programs. For more information about this program see http://www.utexas.edu/ugs/hc
Maria Croyle & Sandra Renteria Joe Dekker Jin Huk Choi	May 27-30, 2009 The Croyle Lab Presents Three Papers on Vaccine Research at National American Society of Gene Therapy Meeting in San Diego Three students from Dr. Croyle's lab had abstracts selected for presentation in the Infectious Diseases and Vaccines Section of the National ASGT meeting. Sandra Renteria, a P3 student who started in the lab prior to studying in the College as part of the Hispanic Center of Excellence program, presented her work titled "Effects of Concentration and Formulation on Adenovirus Stability and Infectious Titer during Actuation from Two Intranasal Delivery Devices". Sandra received a travel scholarship from the College to support her trip and plans to submit this work to a peer-reviewed scientific journal by the end of the fall semester. Joe Dekker, a graduate student in the ICMB program, presented his work titled "An In Vitro and In Vivo Strategy for Optimization of a Recombinant Adenovirus-Based Ebola Vaccine for Nasal Administration". Joe also plans to submit this work for publication soon. Jin Huk Choi, a Pharmaceutics graduate student, also received a travel award from the College to present his work titled "Development of a Recombinant Adenovirus-Based Ebola Vaccine for Oral Administration". Katie Lee, P1 student who also works in the lab, attended the meeting as part of her participation in the UT Intellectual Entrepreneurship Program for undergraduates in the College of Natural Sciences. To read more about Katie's experience in the IE program and her work in the Croyle lab, please visit her page.
Dr. David Curiel, Director of the UAB Gene Therapy Center (left) and Dr. Maria Croyle.	December 11, 2008 Dr. Croyle speaks at the UAB Gene Therapy Center Dr. Croyle spent the day meeting with director Dr. David Curiel and other faculty, post-docs and graduate students actively working on clinical trials for genetic and vaccine-based therapies. The day ended with her seminar entitled, "Pharmacology, Toxicology and Delivery Issues Associated with Recombinant Adenovirus-based Vaccines". The presentation was co-sponsored by the UAB Department of Pharmacology and Toxicology.
Watch UT campaign video featuring Dr. Croyle	May 1, 2008 Croyle Receives Over $2.6 From National and International Granting Agencies to Develop a Vaccine Against Ebola
Piyanuch Wonganan	April 17, 2008 Wonganan Receives Award for Outstanding Research Achievement at College of Pharmacy Celebration of Research Excellence Day. Piyanuch Wonganan, a third year graduate student in Pharmaceutics, received recognition for her work titled "Pharmacology and Toxicology of PEGylated Helper-Dependent Adenovirus in Non-Human Primates". She presented a 15 minute presentation of the work and received a certificate stating the honor. Piyauch was also recognized for this work at the national scientific meeting of the American Society of Gene Therapy.
Evening banquet reception for participants in the biotechnology conference. On the left (back to front): Hyo-Kyung Han (Chosun University), Maria Croyle (University of Texas at Austin), Svetlana Ermankova (Pacific Institute of Bioorganic Chemistry FEB RAS, Vladivostok, Russia), Masahiro Murakami (Osaka Ohtani University, Japan). On the right (back to front): Tetsuya Ozeki (Tokyo University of Pharmacy and Life Sciences, Japan), Xiliang Zha (Fudan University, China), Hoo-Kyun Choi (Chosun University, Korea), Cheol-Hee Choi (Chosun University), Woon-Keun Oh (Chosun University), Hye-Gwang Jeong (Chosun University)	September 10-11, 2007 Dr. Croyle Discusses Virus Infection and Drug Metabolism with International Group of Researchers at Chosun University in South Korea. Dr. Maria Croyle was invited to participate in an international conference titled "Recent Advances and Prospects in the Development of Combined Biotechnology Drugs" held at Chosun University in Gwangju, South Korea. The symposium was sponsored by the College of Pharmacy and the Korean government to foster international collaboration in the area of biotechnology. Dr. Croyle's talk was titled "Impact of Recombinant Viruses on Drug Metabolism".
Dr. Croyle, Dr. Tetsuya Ozeki and his graduate students from the Tokyo University of Pharmacy and Life Sciences as they leave Chosun University and head to Seoul Korea for the national scientific conference BioKorea 2007.	September 12-14, 2007 Dr. Croyle Presents Work on PEGylated Adenoviruses to International Audience at BioKorea 2007 Conference. Dr. Croyle was invited to participate in the international conference by Dr. Hyo-Kyung Han of Chosun University. Croyle and Han met while working as graduate students in the laboratory of Dr. Gordon Amidon at the University of Michigan. Dr. Croyle's talk was titled "Pharmacology and Toxicology of Modified Recombinant Virus for Vaccine and Gene Transfer". Dr. Croyle enjoyed exchanging ideas with conference participants and visiting the many sights in and near Seoul.
Beautiful flowers and tulip fields of Amsterdam	April 22-25, 2007 Croyle Attends Pharmaceutical Sciences World Congress Conference"Optimizing Drug Therapy" An Imperative for World Health- in Amsterdam, The Netherlands. Dr. Croyle discussed with the international audience her work in the area of virus infection and renal and hepatic drug metabolism. Her presentation was titled "A Single Dose of Recombinant Adenovirus Significantly Alters Hepatic and Renal Cytochrome P450 Expression and Function for 14 Days". Dr. Croyle also enjoyed visiting the many sights in and near Amsterdam while attending the conference.