1. J.T. McConville, N. Patel, N. Ditchburn, P. Woodcock, M.J. Tobyn, J.N. Staniforth, Use of a Novel Modified TSI for the Evaluation of Controlled-Release Aerosol Formulations, Drug Development and Industrial Pharmacy, 26(2000) 1191-1198.

2. J.T. McConville, A.C. Ross, A.R. Chambers, G. Smith, A.J. Florence, H.N.E. Stevens, The Effect of Wet Granulation on the Erosion Behavior of an HPMC-Lactose Tablet, Used as a Rate-Controlling Component in a Pulsatile Drug Delivery Capsule Formulation, European Journal of Pharmaceutics and Biopharmaceutics, 57(2004) 541-549.

3. J.T. McConville, A.C. Ross, A.J. Florence, H.N.E. Stevens, Erosion Characteristics of an Erodible Tablet Incorporated in a Time-Delayed Capsule Device, Drug Development and Industrial Pharmacy, 31(2005) 79-89.

4. J.T. McConville, T.C. Carvalho, A.N. Iberg, R.L. Talbert, D.S. Burgess, J.I. Peters, K.P. Johnston, R.O. Williams III, Design and Evaluation of a Restraint-Free Small Animal Inhalation Dosing Chamber, Drug Development and Industrial Pharmacy, 31(2005) 35-42.

5. B.J. Hoeben, D.S. Burgess, J.T. McConville, L.K. Najvar, R.L. Talbert, J.I. Peters, N.P. Wiederhold, B.L. Frei, J.R. Graybill, R. Bocanegra, K.A. Overhoff, P. Sinswat, K.P. Johnston and R.O. Williams III, In Vivo Efficacy of Aerosolized Nanostructured Itraconazole Formulations for the Prevention of Invasive Pulmonary Aspergillosis, Antimicrobial Agents and Chemotherapy, 50(2006) 1552-1554.

6. J.M. Vaughn, J.T. McConville, X. Gao, M.T. Crisp, K.P. Johnston, R.O. Williams III, Supersaturation Produces High Bioavailability of Amorphous Danazol Particles Formed by Evaporative Precipitation into Aqueous Solution and Spray Freezing into Liquid Technologies, Drug Development and Industrial Pharmacy, 32(2006) 559-567.

7. J.T. McConville, K.A. Overhoff, P. Sinswat, J.M. Vaughn, B.L. Frei, D.S. Burgess, R.L. Talbert, J.I. Peters, K.P. Johnston, R.O. Williams III, Targeted High Lung Concentrations of Itraconazole Using Nebulized Dispersions in a Murine Model, Pharmaceutical Research, 23(2006) 901-911.

8. J.M. Vaughn, J.T. McConville, D.S. Burgess, J.I. Peters, K.P. Johnston, R.L. Talbert, R.O. Williams III, Single Dose and Multiple Dose Studies of Aerosolized Itraconazole Nanoparticles, European Journal of Pharmaceutics and Biopharmaceutics, 63(2006) 95-102.

9. T. Purvis, J.M. Vaughn, T.L. Rogers, X. Chen, K.A. Overhoff, P. Sinswat, J. Hu, J.T. McConville, K.P. Johnston, R.O. Williams III, Cryogenic liquids, Nanoparticles, and Microencapsulation, International Journal of Pharmaceutics, 324(2006) 43-50.

10. D.A. Miller, J.T. McConville, W. Yang, R.O. Williams III, J.W. McGinity, Hot-Melt Extrusion for Enhanced Delivery of Drug Particles, Journal of Pharmaceutical Sciences, 96(2007) 361-76. Invited Article.

11. J.M. Vaughn, N.P. Wiederhold, Jason T. McConville, J.J. Coalson, R.L. Talbert, D.S. Burgess, K.P. Johnston, R.O. Williams III, Murine Airway Histology and Alveolar Macrophage Uptake of Inhaled Amorphous Itraconazole, International Journal of Pharmaceutics, 338(2007) 219-224.

12. C.A. Alvarez, N.P. Wiederhold, J.T. McConville, J.I. Peters, L.K. Najvar, J.R. Graybill, J.J. Coalson, R.L. Talbert, D.S. Burgess, R. Bocanegra, K.P. Johnston, R.O. Williams III, Aerosolized Nanostructured Itraconazole as Prophylaxis Against Invasive Pulmonary Aspergillosis, Journal of Infection, 55(2007) 68-74.

13. K.A. Overhoff, J.T. McConville, W. Yang, K.P. Johnston, J.I. Peters, R.O. Williams, Effect of Stabilizer on the Maximum Degree and Extent of Supersaturation and Oral Absorption of Tacrolimus Made by Ultra-Rapid Freezing, Pharmaceutical Research, 25(2008) 167-175.

14. W. Yang, J. Tam, D.A. Miller, J. Zhou, J.T. McConville, K.P. Johnston, R.O.Williams III, High Bioavailability from Nebulized Itraconazole Nanoparticle Dispersions with Biocompatible Stabilizers, Special Edition: Pharmaceutical Nanotechnology, International Journal of Pharmaceutics, 361(2008) 177-188. Invited Article.

15. J. Tam, J.T. McConville, R.O. Williams III, K.P. Johnston, Amorphous
Cyclosporin-A Nanodispersions for Enhanced Pulmonary Deposition and Dissolution, Journal of Pharmaceutical Sciences, 97(2008) 4915-4933.

16. P. Sinswat, K.A. Overhoff, J.T. McConville, K.P. Johnston, Robert O. Williams III, Nebulization of Nanoparticulate Amorphous or Crystalline Tacrolimus - Single-Dose Pharmacokinetics Study in Mice, European Journal of Pharmaceutics and Biopharmaceutics, 69(2008) 1057-1066.

17. Y-J. Son, J.T. McConville, Advancements in Dry Powder Delivery to the Lung, Special Edition: Innovative Inhalation Technologies, Drug Development and Industrial Pharmacy, 34(2008) 948-959. Invited Article.

18. A.B. Watts, J.T. McConville, R.O. Williams III, Current Therapies and Technological Advances in Aqueous Aerosol Drug Delivery, Special Edition: Innovative Inhalation Technologies, Drug Development and Industrial Pharmacy, 34(2008) 913-922. Invited Article.

19. J.T. McConville, S.A. Kucera, T.C. Carvalho, E.M. Hurley, The Stabilization of Ethyl Lactate for Use as a Pharmaceutical Grade Excipient, and the Development of Sensitive Peroxide Assay, Pharmaceutical Technology - In Press.

20. S. Thitinan, J.T. McConville, Interferon Alpha Delivery Systems for the Treatment of Hepatitis C, International Journal of Pharmaceutics - In Press. Invited Article.

21. J.T. McConville, B. O'Mahony, B. Lindsay, T. Jones, A.C. Ross, A.J. Florence, C.G. Wilson, H.N.E. Stevens, A Pharmacoscintigraphic Study of a Time-Delayed Capsule Formulation in Eight Healthy Male Volunteers, Journal of Pharmaceutical Sciences - Under Peer Review.

22. S-F. Jang, J.T. McConville, Targeted and Prolonged Drug Delivery to the Gastrointestinal Tract, Journal of Pharmacy and Pharmacology - In Preparation.

23. Y-J. Son, J.T. McConville, A Standardized Dissolution Test Method for Inhaled Pharmaceutical Formulations, Drug Development and Industrial Pharmacy - In Preparation.

Other Published Contributions

1. Featured Article: Recent Trends in Oral Drug Delivery, The Drug Delivery Companies Report, PharmaVentures, Oxford, UK, Autumn/Winter (2005) 24-27. Invited Article.

2. Preface for Advanced Drug Formulation Design to Optimize Therapeutic Outcome, Eds. Robert O. Williams III, David R. Taft, J.T. McConville, Informa Healthcare, New York, NY, September, 2007. Invited Article.

3. Jason T. McConville, Nathan P. Wiederhold, Invasive Pulmonary Aspergillosis: Therapeutic and Prophylactic Strategies, In Advanced Drug Formulation Design to Optimize Therapeutic Outcomes, Eds. Robert O. Williams III, David R. Taft, J.T. McConville, Informa Healthcare, New York, NY, September 2007. Invited Article.

4. Jason T. McConville, Nathan P. Wiederhold, Antifungal Prophylaxis to the Lung Using Itraconazole, Inhalation, 1:1(2007) 6-9. Invited Article.

5. M. Teresa Carvajal, David Cipolla, Mark Copley, Jason T. McConville, Highlights from RDD 2008: Inhalation Reports on Some of the Most Interesting Research Presented at the Most Recent Respiratory Drug Delivery Meeting, Inhalation, 2:3(2008) 18-20. Invited Article.

7. Preface for Innovative Inhalation Technologies, Special Themed Edition of Drug Development and Industrial Pharmacy, Guest Editors: Jason T. McConville, Fiona J. McInnes, Alistair C. Ross, 34(2008) 911-912. Invited Article.

8. Featured News Article: University of Texas at Austin Pharmacy Researcher Works to Lower Carbon Footprint of Pharmaceuticals, www.BiobasedNews.com, August, 2008.

9. Yoen-Ju Son, Jason T. McConville, Dissolution Testing for Inhalation Formulations, Inhalation, In Press. Invited Article.

Published Abstracts

1. An In Vitro Method for Evaluation of Dry Powder Inhaler Formulations using a Novel Modified Twin Stage Impinger, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Boston, MA, November, 1997.


2. A Novel Ex Vivo Method for Determining Diffusion Rates of Dry Powder Inhaler Formulations using an Isolated Perfused Guinea Pig Lung Model, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Boston, MA, November, 1997.


3. The Comparison of Two Delivery Techniques for Dosing an Isolated Perfused Guinea Pig Lung (IPGPL), Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Francisco, CA, November, 1998


4. An In Vitro Method for Evaluation of Lung Deposition and Drug Diffusion from Dry Powder Formulations using a Modified Twin Stage Impinger, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Francisco, CA, November, 1998.


5. Preclinical Evaluation of an Isotretinoin (iso) Powder Formulation for Aerosol Administration in Lung Cancer Chemoprevention, Proceedings of the American Association of Cancer Research, Philadelphia, PA, April, 1998.


6. Effect of Process Variables on the Time-delayed Release from a Capsule Based Delivery Device, Proceedings of the 23rd Joint Research Seminar, Dublin, Ireland, June, 2000.


7. Effect of Process Variables on Drug Release from a Time-Delayed Capsule Delivery System, Proceedings of the 137th British Pharmaceutical Conference, Birmingham, United Kingdom, September, 2000.


8. Processing Induced Variability of Time-delayed Delivery from a Pulsatile Capsule Device, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Indianapolis, IN, October, 2000.


9. Microwave Dielectric Analysis of Wet Granulations for Erodible HPMC Tablets, Proceedings of the 138th British Pharmaceutical Conference, Glasgow, United Kingdom, September, 2001.


10. The use of Microwave Analysis to Describe the Effect of a Wet Granulation Processing Technique, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Denver, CO, October, 2001.


11. Gamma Scintigraphic Visualisation of Drug Release from a Time-Delayed Capsule, Proceedings of the 6th US-Japan Drug Delivery Symposium, Honolulu, HI, November, 2001.


12. Gamma Scintigraphic Investigation of Drug Release from a Time-Delayed Capsule, Proceedings of the 29th International Symposium on Controlled Release of Bioactive Materials, Seoul, Korea, June, 2002.


13. Preparation of Water-impermeable Capsule Bodies for a Pulsatile Drug Delivery System, Proceedings of the 139th British Pharmaceutical Conference, Manchester, United Kingdom, September, 2002.


14. Time Delayed Delivery of Theophylline, Proceedings of the 139th British Pharmaceutical Conference, Manchester, United Kingdom, September, 2002.


15. The Suitability of a Capsule Component for use with a Pulsed Release Drug Delivery Device, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Toronto, Canada, November, 2002.


16. Gastrointestinal Transit and Release of Time-Delayed Delivery Capsules, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Toronto, Canada, November, 2002.


17. A Study to Investigate the effects of Food Administration Post-gastric Emptying on a Time-delayed Formulation in Healthy Volunteers using Gamma Scintigraphy, Proceedings of the 30th International Symposium on Controlled Release of Bioactive Materials, Glasgow, United Kingdom, June, 2003.


18. Physiochemical Properties of Itraconazole Produced by Spray-Freezing into Liquid Process, 1st European Federation for Pharmaceutical Sciences Conference on Optimizing Drug Delivery and Formulation: New Challenges in Drug Delivery, Versailles, France, September, 2003.


19. Controlling Particle Characteristics of Itraconazole Powders Produced by Spray-freezing into Liquid - Organic Solution Versus Emulsion Liquid Feed Solutions, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Salt Lake City, UT, October, 2003.


20. Nebulisation of a Suspension Containing Itraconazole Prepared by Evaporative Precipitation into Aqueous Solution, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Salt Lake City, UT, October, 2003.


21. Spray Freezing into Liquid of Itraconazole for Pulmonary Delivery, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Salt Lake City, UT, October, 2003.


22. Enhanced Solubility and Dissolution of Itraconazole Prepared by the Spray Freezing into Liquid Technique, Proceedings of the 31st International Symposium on Controlled Release of Bioactive Materials, Honolulu, HI, June, 2004.


23. The Use of Antioxidants to Stabilize Ethyl Lactate, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Baltimore, MD, November, 2004.


24. Design of a Restraint-Free Small Animal Dosing Chamber for Inhalation and Investigation of Drug Distribution Within the Chamber, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Baltimore, MD, November, 2004.


25. Miscibility of Hydrophilic Polymers and Surfactants with Polyethylene Oxide in Hot-melt Extruded Tablets Containing Poorly Water Soluble Drug, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Baltimore, MD, November, 2004.


26. Delivery of Poorly Water Soluble Drugs using Nebulization, Proceedings of the 15th Drug Delivery to the Lung Conference, London, United Kingdom, December, 2004.


27. Improved Dissolution Rate and Bioavailability through the Formation of a Highly Miscible Binary Mixture, Proceedings of the 32nd International Symposium on Controlled Release of Bioactive Materials, Miami, FL, June, 2004.


28. Delivery of Nebulized Itraconazole Nanoparticles in the Murine Model, Proceedings of the Respiratory Drug Delivery (RDD IX) Europe Conference, Paris, France, May, 2005.


29. Particle Engineering for Rapid Dissolution Rates of Poorly Water Soluble Drugs, American Institute of Chemical Engineers (AIChE) Annual Meeting, Cincinnati, OH, October, 2005


30. Investigation of Dissolution Properties of Microcrystalline or Stabilized Amorphous Particles of Itraconazole in Melt Extruded Solid Dispersions, Joint Symposium on the Future Prospects of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan, October, 2005.


31. Characterization of Nebulized Itraconazole Nanoparticles and Delivery to the Murine Lung, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Nashville, TN, November, 2005.


32. Treatment of Acute Pulmonary Aspergillosis with Nebulized Itraconazole in the Murine Model, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Nashville, TN, November, 2005.


33. Improved Danazol Supersaturation and Oral Bioavailability via Formulation into an Amorphous Solid Solution, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Nashville, TN, November, 2005.


34. Investigation of Dissolution Properties of Microcrystalline or Stabilized Amorphous Particles of Itraconazole in Melt Extruded Solid Dispersions, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Nashville, TN, November, 2005.


35. Treatment of Pulmonary Aspergillosis using Nebulized Itraconazole Nanoparticles prepared using Particle Engineering Technologies, Proceedings of the 16th Drug Delivery to the Lung Conference, London, United Kingdom, December, 2005.


36. In Vivo Efficacy of Aerosolized Nano-structured Itraconazole (ITZ) Formulations for the Prevention of Invasive Pulmonary Aspergillosis (IPA), 45th Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, DC, December 2005 (originally scheduled for New Orleans, September, 2005).


37. Single Dose Variability and Multi-Dose Studies of Nebulized Itraconazole in a Murine Model, Proceedings of the Respiratory Drug Delivery (RDD X) Conference, Boca Raton, FL, April, 2006.


38. Murine Airway Histology and Alveolar Macrophage Uptake of Inhaled Amorphous Itraconazole (Itra), Proceedings of The American Thoracic Society International Conference, San Diego, CA, May, 2006.


39. Particle Engineering and Formulation for Enhanced Bioavailability of Poorly Water Soluble Drugs, Proceedings of the Particles 2006 Conference, Orlando, FL, May, 2006.


40. Sustained Lung Concentrations of Itraconazole using Nebulized Dispersions in a Murine Model, Proceedings of the 32nd International Symposium on Controlled Release of Bioactive Materials, Vienna, Austria, July, 2006.


41. Aerosolized Itraconazole (ITZ) as Prophylaxis against Invasive Pulmonary Aspergillosis (IPA) due to Aspergillus fumigatus, Proceedings of the American College of Clinical Pharmacy Annual Meeting, San Antonio, TX, November, 2006.


42. In-vitro and In-vivo Comparison of Melt Extruded Particulate Dispersions of PVP and HPMC-Stabilized Nano-Structured Amorphous Itraconazole Particles, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Antonio, TX, October, 2006.


43. Antisolvent Precipitation of Cyclosporin A Nanoparticles for Enhanced Pulmonary Delivery, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Antonio, TX, October, 2006.


44. Immunological Response and Alveolar Macrophage Uptake of Inhaled Amorphous ITZ, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Antonio, TX, October, 2006.


45. In Vitro and In Vivo Validation of a High-Concentration Pre-Clinical Rodent Dosing Apparatus for Inhalation, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Antonio, TX, October, 2006.


46. A Novel In Vitro Pulmonary Dissolution Testing Method for Controlled Release Inhalation Formulations, Proceedings of the 33rd International Symposium on Controlled Release of Bioactive Materials, Long Beach, CA, July, 2007.


47. The Swelling Properties of Walocel-HM (Hypromellose) in 100% Ethanol, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Diego, CA, November, 2007.


48. A Novel In Vitro Dissolution Testing Method for Inhalation Formulations, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Diego, CA, November, 2007.


49. In Vitro Determination of Gastric Mucoadhesion for Hypromellose Formulations, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, San Diego, CA, November, 2007.


50. Development of a Standardized In Vitro Pulmonary Dissolution Testing Method, Proceedings of the 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain, April 2008.


51. Development of a Standardized Dissolution Test for Inhalable Formulations, Proceedings of the Respiratory Drug Delivery (RDD XI) Conference, Scottsdale, AZ, May, 2008.


52. In Vitro Determination of Gastrointestinal Mucoadhesion Formulations, Proceedings of the 34th International Symposium on Controlled Release of Bioactive Materials, New York, NY, July, 2008.


53. Aerosolized Voriconazole (VRC) as Prophylaxis against Invasive Pulmonary Aspergillosis (IPA) due to Aspergillus fumigatus, 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/Infectious Diseases Society of America 46th Annual Meeting, Washington, DC, October 2008.


54. Preliminary Studies for Rapidly Disintegrating Mini-Tablets for Enteric Coated Oral Delivery, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.


55. Gender and Race-Based Disparities in the Proportion of Hepatitis C Patients that are Co-Infected with HIV/AIDS in The 1996-2005 US National Hospital Discharge Survey, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.


56. Low Concentration Range Determination of API 31510 using High Performance Liquid Chromatography (HPLC), Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.


57. Major Sites of Pulmonary Malignancy and Associated Health Outcomes for Lung Cancer Patients in the 1996-2005 National Hospital Discharge Survey (NHDS), Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.


58. Improvements of an In Vitro Dissolution Test Method For Dry Powder Inhalation Formulations, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.


59. Aerosol Characterization and Single-Dose Pharmacokinetic Analysis of Nebulized Voriconazole Solution, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.


60. Investigation of Nebulized Dose and Inhaled Dose of Itraconazole Dispersions in a Nose-Only Rodent Dosing Chamber, Proceedings of the Annual Meeting of the American Association of Pharmaceutical Scientists, Atlanta, GA, November, 2008.