Photo of Pearlman

Pearlman, Robert, Ph.D.
Coulter R. Sublett Chair
PHR 4.214F

Research Interests

It is estimated that, for every new drug that reaches the market place, more than 8,000 potential drug candidates were synthesized, tested to varying extents, and judged to be unsuitable. Not surprisingly, the pharmaceutical industry is extremely interested in computer-based methods for improving the efficiency of the drug discovery process. The primary mission of our Laboratory for Molecular Graphics and Theoretical Modeling is to develop novel theory and software for computer-assisted drug design (CADD). We address both of the fundamental aspects of drug action: transport to the biophase and interaction with the receptor. Research assistants acquire a broad background in physical chemistry, computational chemistry, numerical analysis and computer programming and utilize state-of-the-art hardware and software in a laboratory supported, in part, by the proceeds resulting from the commercial distribution of software which we have developed.

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Last Reviewed: June 15, 2009

Division Information

Mailing Address:
Pharmaceutics Division
College of Pharmacy
The University of Texas
at Austin
2409 University Ave.
Stop A1900
Austin, TX, USA

Email Address: pharmacy


Researchers Offer Promise Through Enhanced Drug Delivery

Enhancing drug-delivery technologies can help in curing and treating diseases such as cancer, cardiovascular diseases, diabetes, fungal, respiratory and infectious diseases and treatment after organ transplants to prevent rejection.

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