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Pharmacotherapy

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Kuhn, John G., Pharm.D.
Emeritus Professor
of Pharmacotherapy
210- 567-8340
kuhn@uthscsa.edu


Summary & Research Interests

The research in our laboratories is concentrated on deriving information related to the clinical pharmacology of anticancer agents.  To accomplish our research objectives, we establish suitable analytical (HPLC, CE, LC/MS) or molecular (PCR, Western, Elisa) methods for the measurement of the compounds in biological fluids or tissue.  We explore the relationships between the pharmacokinetic parameters (clearance, AUC) of the agent and their biological targets, activity and/or toxicity.  These correlations permit the development of rational dosing and scheduling regimens for the optimization of the compound's therapeutic index.     We also evaluate genetic variations responsible for drug metabolism, transport or target affinity.  The laboratories serve as the Pharmacology Core for the North American Brain Tumor Consortium (NABTC).


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More information about Dr. Kuhn
> Selected Publications

Last Reviewed: September 18, 2008

Division Information

Mailing Address:
Pharmacotherapy
Education & Research Ctr.
College of Pharmacy
The University of Texas
Health Science Center
7703 Floyd Curl Drive - MC 6220
San Antonio, TX
78229-3900
USA

Email Address: pharmacy
@austin.utexas.edu

Phone:
1-210-567-8355


Frei to Lead Division

Dr. Chris Frei has been appointed as division head for the college's Pharmacotherapy Division which is located on the UT Health Science Center San Antonio campus.

Read more about Frei's appointment

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