Leroy C. Knodel, Pharm.D.

Associate Professor

(B.S., University of Kentucky, 1976; Pharm.D. and Clinical Residency, University of Kentucky, 1980)
Clinical Associate Professor

knodel@uthscsa.edu

Practice and Research Interests Leroy C. Knodel is the Director of the Drug Information Service at the University of Texas Health Science Center at San Antonio (UTHSCSA), clinical clerkship regional coordinator for San Antonio, and coordinator of the M.S./Ph.D. in Pharmacy (Pharmacotherapy) residency program. Dr. Knodel's primary teaching emphasis in the College of Pharmacy is in the areas of literature evaluation, study design, biostatistics, and GI pharmacotherapeutics. He also serves as a lecturer in the UTHSCSA Medical and Dental Schools. In addition to his institutional responsibilities as a member of the Audie L. Murphy Veterans Administration Hospital Pharmacy and Therapeutics Committee, and as a consultant to the University Health System (Bexar county, Texas) Pharmacy and Therapeutics Committee and Drug Usage Evaluation Committee, Dr. Knodel is active in various state and local health care organizations. Since 1992 Dr. Knodel has served as a member and vice-chairman of the Texas Department of Health Drug Utilization Review Committee. For over 10 years he has served on the Board of Directors of Community Clinic, a United Way-funded agency providing medical and counseling services to low-income individuals in San Antonio. Additionally, he serves as the clinic's pharmacist-in-charge (volunteer). Dr. Knodel's primary scholarly activities relate to application of computer technologies in improving drug information storage, retrieval, and dissemination.

Recent Publications and Presentations

Clinical and Economic Considerations in the Use of COX-2 Specific Inhibitors@, Western Branches, Canadian Society of Health-System Pharmacists, 27th Annual Banff Seminar, Calgary, Alberta, Canada, March 17, 2001.

New Drugs of 2000,@ 49th Annual Postgraduate Pharmacy Seminar, The University of Texas at Austin College of Pharmacy, Austin, Texas, September 15, 2001.

Advances in Acid Suppression Therapy@, Annual Installation of Officers, Bexar County Pharmacy Association, San Antonio, Texas, February 8, 2001.

Evaluation of COX-1 and COX-2 Inhibitors@, Department of Defense Pharmacoeconomics/Pharmacy Benefit Conference, San Antonio, Texas, January 8, 2001.

The Pharmacodynamics of Proton Pump Inhibitors@, Houston Gastroenterology Summit, Houston, Texas, October 7, 2000.

Therapeutic Approaches in the Management of GERD: An Update,@ Central Texas Society of Hospital Pharmacists, San Antonio, Texas, August 8, 2000.

Cox-2 Technology: A Year in Review. The Promise and the Potential,@ Longs Drug Stores Pharmacy Managers Meeting 2000, Palm Springs, California, May 25, 2000.

Overview of the Pharmacology and GI Safety and Tolerability of COX-2 Inhibitors, @ Satellite Symposium entitled ACOX-2 Technology: A Year in Review. The Promise and the Potential, @ American Pharmaceutical Association Annual Meeting, Washington, D.C., March 13, 2000.

The Economic Burden of Arthritis and Cost Issues Related to the Use of COX-2 Inhibitors, @ Satellite Symposium entitled ACOX-2 Technology: A Year in Review. The Promise and the Potential, @ American Pharmaceutical Association Annual Meeting, Washington, D.C., March 13, 2000.

Knodel LC. Sexually transmitted diseases. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 4th edition. New York: Appleton & Lange, 1999.

Editor, Nonprescription Products: Formulations & Features '98-99. A Companion to the Handbook of Nonprescription Drugs (12th edition, 1998). Washington DC: American Pharmaceutical Association, 1998.

Seltzer JK, Kurt TL, Knodel LC, et al. Drug utilization review of sedative/hypnotic agents in Texas Medicaid patients. J Am Pharm Assoc 2000;40:495-9.

Horton PM, Knodel LC. Dietary supplements containing ephedrine: Is a natural high a safe high? Toxic Substance Mechanisms 1998; 17:95-97.

Dugan DJ, Knodel LC. Alcohol and drugs: a potentially dangerous combination. Toxic Substance Mechanisms 1997;16:385-387.

Hatfield CL, Knodel LC, Talbert RL. Olestra: an ideal substitute for dietary fat? Toxic Substance Mechanisms 1997;16:209-11.

Knodel LC. Adverse health consequences of cigarette smoking also include drug interactions. Toxic Substance Mechanisms 1997;16:87-9.