Student Information Training Programs Research Centers

Pharmacology & Toxicology

Research and Graduate Training Faculty

Photo

Bratton, Shawn B., Ph.D.
Adjoint Associate Professor of Pharm./Tox.
BME 3.510E
512-471-1735
sbbratton@austin.utexas.edu


Lab Alumni

Photo

Youngeun Choi, Ph.D.
Graduate Student
College of Pharmacy

Email:toyoung@gmail.com
Current Position: Postdoctoral fellow; Dana-Farber Cancer Institute / Harvard Medical School, Boston, MA; Advisor: Dipanjan Chowdhury

As a grad student in the Bratton Lab, my project focused primarily on understanding how two related inhibitor of apoptosis proteins, cIAP1 and cIAP2, suppressed apoptosis through their distinct interactions with the effector caspases- 3 and -7.

Education:
B.S.: Pharmacy (Sookmyung Women's University, Seoul, South Korea)
M.S.: Analytical Pharmaceutics (Sookmyung Women's University, Seoul, South Korea)
Ph.D.: Pharmacy (The University of Texas at Austin, Austin, TX)



Photo

Madhavi Malladi, Ph.D.
Research Associate
College of Pharmacy

Email: mm3895@columbia.edu
Current Position: Postdoctoral fellow; Columbia University, New York, NY; Advisor: Riccardo Dalla-Favera

Caspases are activated in response to various cell death stimuli and inhibitor of apoptosis (IAP) proteins can bind and inhibit caspases. My research was primarily focused on understanding the mechanisms by which IAPs and their antagonists regulate caspase activation using Drosophila a model system.

Education:
B.S.: Agricultural Sciences (A. N. G. R Agricultural university, Hyderabad, India)
M.S.: Plant Sciences (Texas A&M - Kingsville, Dr. Robert Morgan)
M.S.: Biology (Texas A&M - Kingsville, Dr. Rafael Perez-Ballestero)
Ph.D.: Cell and Molecular Biology (The University of Texas at Austin, Austin, TX)


Photo

Srinivas Malladi, Ph.D.
Graduate Student
Cell and Molecular Biology

Email: MalladiS@mskcc.org
Current Position: Postdoctoral fellow; Memorial Sloan-Kettering Cancer Center, New York, NY; Advisor: Joan Massague

During stress-induced apoptosis, mitochondrial outer membrane permeabilization results in the release of cytochrome-c into the cytosol, leading to the formation of a large caspaseactivating complex, termed the "apoptosome". My project was focused on understanding the mechanisms of caspase-9 processing and activation within the apoptosome.

Education:
B.S.: Agricultural Sciences (A. N. G. R Agricultural university, Hyderabad, India)
M.S.: Agri-Business Management (Texas A&M - Kingsville, Dr. Donald Nixon)
M.S.: Biochemistry (Texas A&M - Kingsville, Dr. Gonzalez-Garcia)
Ph.D.: Cell and Molecular Biology (The University of Texas at Austin, Austin, TX)


Photo

Jaekyoung Son, Ph.D.
Graduate Student
College of Pharmacy

Email: mr2710@hotmail.com
Current Position: Postdoctoral fellow; Dana-Farber Cancer Institute / Harvard Medical School, Boston, MA; Advisor: Alec Kimmelman

My project focused on TRAIL, a member of the TNF receptor superfamily. I invested the intracellular mechanisms responsible for TRAIL resistance in human prostate cancer cells, with a particular focus on the role of p38 MAPKs in this process.

Education:
B.S.: Biology (Hankuk University of Foreign Studies, South Korea)
M.S.: Molecular Biology (Hankuk University of Foreign Studies, South Korea) Ph.D.: Pharmacy (The University of Texas at Austin, Austin, TX)


Photo

Shankar Varadarajan, Ph.D.
Graduate Student
Cell and Molecular Biology

Email: shankar.varadarajan@gmail.com
Current Position: Postdoctoral fellow; Medical Research Council - Toxicology Unit, Leicester, UK; Advisor: Gerald M. Cohen

As a grad student in the Bratton Lab, I worked on two different research projects; one project dealt with the role of p38 MAPKs in regulating autophagy and lysosomal biogenesis, while the other project involved TNFR1 signaling and receptor trafficking mechanisms.

Education:
B.S.: Pharmacy (The TN Dr.MGR Medical University, Chennai, India)
M.S.: Biotechnology (Birla Institute of Technology and Sciences, Pilani, India)
Ph.D.: Cell and Molecular Biology (The University of Texas at Austin, Austin, TX)


More information about Dr. Bratton
> CV
> Recent Publications
> Research Images
> Lab Members
> Lab Pictures
> Return to Bratton's Home Page


(Download PDF Reader.)

Last Reviewed: December 13, 2010

Division Information

Mailing Address:
Pharmacology & Toxicology
College of Pharmacy
The University of Texas
at Austin
107 W. Dean Keeton
Stop C0875
Austin, TX, USA
78712

Email Address: pharmtox
@austin.utexas.edu

Phone: 512-471-5158


Erickson Authors New Book

"Drugs, the Brain and Behavior" is co-authored by Dr. Carlton Erickson, the college's associate dean for research and graduate studies, and Dr. John Brick, executive director of Intoxikon International.

> Read more about Dr. Erickson's new book.


Gore receives SEBM award

Andrea Gore is named to the SEBM Distinguished Scientist Award.

> Read more about Dr. Gore's new award.

index of the major headings: a b c d e f g h i j k l m n o p q r s t u v w x y z