Phone: (512) 471-1090
Fax: (512) 475-6088
duvauchelle@mail.utexas.edu
Spotlight: Grant for Cocaine Addiction Study
Research Interests
Exploring neural mechanisms of reward using behavioral, pharmacological, neurochemical & immunological methodologies
Three general research areas are being explored:
These studies have revealed that both brief and lengthy drug use result in profound neural and behavioral changes. The results of these studies can assist in designing individualized treatment options for patients with varying drug use experience.
Recent Publications/Submissions
Olsen, C.M. and Duvauchelle, C.L. Prefrontal cortex D1 modulation of the reinforcing properties of cocaine. Brain Research, 1075, 229-235, 2006.
Reveron, M.E., Maier, E.Y. and Duvauchelle, C.L. Experience-dependent changes in temperature and behavioral activity induced by MDMA. Physiology and Behavior, 89, 358-363, 2006.
D'Souza, M.S. and Duvauchelle, C.L. Comparing nucleus accumbens and dorsal striatal dopamine responses to self-administered cocaine in naïve rats. Neuroscience Letters, 408 (2),146-150, 2006.
Ikegami, A., Olsen, C.M., D'Souza, M.S. and Duvauchelle, C.L. Experience-dependent effects of cocaine self-administration/conditioning on prefrontal and accumbens dopamine responses. Behavioral Neuroscience, 121 (2) 389-400, 2007.
Seiwell, A.P., Reveron, M.E. and Duvauchelle, C.L. Increased accumbens Cdk5 expression in rats after short-access to self-administered cocaine, but not after long-access sessions, Neuroscience Letters, 417, 100-105, 2007.
Dickerson,, S.M., Walker, D.M. Reveron, M.E. Duvauchelle, C.L. and Gore, A.C. Self-administration of the recreational drug ecstasy disrupts the hypothalamic-pituitary-gonadal reproductive axis in adult male rats. Neuroendocrinology, In Press, 2008.
D'Souza, M.S. and Duvauchelle, C.L. Certain or uncertain cocaine expectations influence accumbens dopamine responses to self-administered cocaine and non-rewarded operant behavior. European Neuropsychopharmacology, 18, 628-638, 2008.
Howard, E.C., Scheir, C.J., Duvauchelle, C.L., Gonzales, R.A. Intravenous ethanol infusion effects on dopamine in the nucleus accumbens core and shell. Neuroscience, 154,1042-1053, 2008.
Meier, E. Y., Ledesma, R. T., Seiwell, A.P. and Duvauchelle, C.L. Diazepam alters cocaine self-administration, but not cocaine-stimulated locomotion or basal nucleus accumbens dopamine, Pharmacology Biochemistry & Behavior, In Press.
Feduccia, A.A. and Duvauchelle, C. L. Auditory stimuli enhance MDMA-conditioned reward and MDMA-induced nucleus accumbens dopamine, serotonin and locomotor responses. Brain Research Bulletin, In Press.
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