Our research focuses on understanding the biological bases of addiction. We use a combination of models that are associated with increased addiction liability, such as that associated with age (i.e. adolescence), naturally-occurring within outbred populations (i.e. inter-individual differences), or induced by exposure to drugs and to stress. Throughout our studies, we use a systems-approach, combining complementary levels of analysis, which include molecular (protein expression), cellular (neuronal activity and synaptic transmission using in vivo and ex vivo electrophysiology), anatomical (optogenetics and functional neuroanatomy), and behavioral studies (self-administration). By combining these levels of analysis, it is possible to answer questions of behavioral relevance at multiple levels, in the hope of gaining more insight on the mechanisms and treatment strategies for addiction.
Pharmacology & Toxicology
College of Pharmacy
The University of Texas
107 W. Dean Keeton
Austin, TX, USA
Email Address: pharmtox
Dr. Som Mukhopad-
hyay led the research team that focused on the gene SLC30A10 and its role as a "door opener" in helping to remove elevated levels of manganese from cells. The study was published in the Oct. 15, 2014 issue of The Journal of Neuroscience.
"Drugs, the Brain and Behavior" is co-authored by Dr. Carlton Erickson, the college's associate dean for research and graduate studies, and Dr. John Brick, executive director of Intoxikon International.
Andrea Gore is named to the SEBM Distinguished Scientist Award.