Student Information Training Programs Research Centers

Pharmacology & Toxicology

Research and Graduate Training Faculty


Mills, Edward M., Ph.D.
Associate Professor of Pharm./Tox.
Bergen-Brunswig Fellow
BME 3.510D

Current Lab Members

Shohei Kohno, Ph.D
Postdoctoral Scientist
College of Pharmacy

My projects focus on the role of uncoupling proteins and mitochondrial metabolism in the regulation of muscle physiology and pathology.

Graduate Student, Ph.D. Candidate
College of Pharmacy

Malignant cells display whole scale bioenergetic changes compared to normal cells that are typified by increased glycolysis and decreased mitochondrial oxidative phosphorylation / respiration.  Recent evidence suggests that this phenotype promotes the use of mitochondria as biosynthetic machines for cancer cell growth.  To better understand the relationships between changes in mitochondrial metabolism and carcinogenesis, our lab generated hemizygous mice expressing a skin-targeted uncoupling protein 3 construct that show increased cutaneous respiration and potent cancer resistance.  My project is focused on the mechanisms by which UCP3 antagonizes skin cancer development.

B.A. Biology (minor Biochemistry), Carleton College, Northfield, MN

Graduate Student
College of Pharmacy

Heat shock proteins (HSPs) are involved in the cellular response to noxious stimuli such as toxicity, oxidative stress, hyperthermia and inflammation.  A recently characterized mitochondrial HSP named cvHSP is expressed most highly in the heart, skeletal muscle, and adipose tissues.  My project focuses on exploring the physiological role of HSP with specific emphasis on protein-protein interactions with mitochondrial proteins and its effects on mitochondrial metabolism.

B.S. Biology, Rice University, Houston, TX

More information about Dr. Mills
> Publications
> Lab Alumni
> Research Images
> Lab Photos
> Student Support and Grants
> Return to Mills' Home Page

Last Reviewed: March 27, 2014

Division Information

Mailing Address:
Pharmacology & Toxicology
College of Pharmacy
The University of Texas
at Austin
107 W. Dean Keeton
Stop C0875
Austin, TX, USA

Email Address: pharmtox

Phone: 512-471-5158

Parkinson Gene Link May Aid Battle Against Disease

Dr. Som Mukhopad-
hyay led the research team that focused on the gene SLC30A10 and its role as a "door opener" in helping to remove elevated levels of manganese from cells. The study was published in the Oct. 15, 2014 issue of The Journal of Neuroscience.

> Read more about Dr. Mukhopadhyay's research.

Erickson Authors New Book

"Drugs, the Brain and Behavior" is co-authored by Dr. Carlton Erickson, the college's associate dean for research and graduate studies, and Dr. John Brick, executive director of Intoxikon International.

> Read more about Dr. Erickson's new book.

Gore receives SEBM award

Andrea Gore is named to the SEBM Distinguished Scientist Award.

> Read more about Dr. Gore's new award.

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