Steve (Yichen) Lin
Postdoctoral Fellow
yichen.lin@mail.utexas.edu
512-471-9171

Project:
Functional spermatogenesis relies heavily on the maintenance of dynamic interactions between Sertoli cells and germ cells of the seminiferous epithelium. Although only a low basal level of germ cell apoptosis occurs in adult animals under physiological conditions, widespread apoptosis occurs during the first round of spermatogenesis during the peri-pubertal period. My project is focus on investigating the functional significance of death ligand/receptor systems in the testis during this critical developmental time period.

See also Yichin Lin's Publications (PDF format).

Education:
B.S.: Agronomy (National Chung-Hsing University, Taiwan)
M.S.: Botany -- Plant physiology and molecular biology (National Taiwan University, Taiwan, Dr. Yih-Ming Chen)

Project: Cisplatin is a common and effective treatment for various tumors; though not without side effects. One of which is prolonged infertility in male patients. The mechanisms of this toxicity are not fully understood, and a critical need exists to determine the biology involved so that patients might maintain fertility while still achieving effective tumor elimination. It is known that exposure to cisplatin induces widespread germ cell apoptosis; however, this well characterized cell death does account for the protracted period of infertility. My research examines the possible implications of cisplatin-induced damage to spermatogonial stem cells and Sertoli cells in patient infertility.

Education: B.S.: Biology (The University of Texas at Arlington)