Wright, C.W. and Duckett, C.S. 2009. The aryl hydrocarbon nuclear translocator alters CD30-mediated NF-kB-dependent transcription. Science (in press).
Csomos, R.A., Wright, C.W., Galban, S., Oetjen, K.A., and Duckett, C.S. 2009. Two distinct signaling cascades target the NF-kB regulatory factor c-IAP1 for degradation. Biochemical Journal (in press).
Galban, S, Hwang, C., Rumble, J.M., Oetjen, K.A., Wright, C.W. and Duckett, C.S. 2008. Cytoprotective effects of IAPS revealed by a small molecule IAP antagonist. Biochemical Journal (in press).
Rumble, J.M., Csomos, R.A., Wright, C.W., Mak, T.W., and Duckett, C.S. 2008. Apoptotic sensitivity of murine IAP-deficient cells. Biochemical Journal, 415, 21-25.
Wright, C.W. and Duckett, C.S. 2008. New Insights into the Function of IAP Proteins: Modulation of the Myc/Max/Mad Network. Developmental Cell, 14, 3-4
Hwang C., Giri, V.N., Wilkinson, J.C., Wright, C.W., Wilkinson, A.S., Cooney, K.A., and Duckett, C.S. 2008. EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor. Breast Cancer Research and Treatment, 107, 235-242
Wright, C.W., Rumble, J.M., and Duckett, C.S. 2007. CD30 activates both the canonical and alternative NF-kB pathways in anaplastic large cell lymphoma cells. Journal of Biological Chemistry, 282, 10252-10262
Wright, C.W. and Duckett, C.S. 2005. Re-awakening the cellular death program in neoplasia through the therapeutic blockade of IAP function. Journal of Clinical Investigation, 115, 2673-2678
Wright, C.W., Penabaz, T., Means, J.C., and Clem, R.J. 2005. The baculovirus anti-apoptotic protein Op-IAP does not inhibit Drosophila caspases or apoptosis in Drosophila S2 cells and instead sensitizes S2 cells to virus-induced apoptosis. Virology, 335, 61-71
Wright, C. W. and Clem, R. J. 2002. Sequence requirements for Hid binding and apoptosis regulation in the baculovirus inhibitor of apoptosis Op-IAP: Hid binds Op-IAP in a manner similar to Smac Binding of XIAP. Journal of Biological Chemistry, 277, 2454-2462
Pharmacology & Toxicology
College of Pharmacy
The University of Texas
107 W. Dean Keeton
Austin, TX, USA
Email Address: pharmtox
Dr. Som Mukhopad-
hyay led the research team that focused on the gene SLC30A10 and its role as a "door opener" in helping to remove elevated levels of manganese from cells. The study was published in the Oct. 15, 2014 issue of The Journal of Neuroscience.
"Drugs, the Brain and Behavior" is co-authored by Dr. Carlton Erickson, the college's associate dean for research and graduate studies, and Dr. John Brick, executive director of Intoxikon International.
Andrea Gore is named to the SEBM Distinguished Scientist Award.