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Drug Dynamics Institute Cores

Overview
Message from the Director,
Carla Van Den Berg, Pharm.D.

TherapeUTex provides novel and innovative solutions in the modeling, evaluation and development of therapeutically active agents utilizing state of the art translational research. A diverse cross-section of faculty from The University of Texas College of Pharmacy created TherapeUTex making their novel preclinical models and evaluation methodologies for drug development available to scientists on a broad basis.

TherapeUTex is part of the Drug Dynamics Institute, which promotes collaboration with University of Texas faculty, Texas Institute for Drug Diagnostics and Development (TI3D) investigators, Austin Technology Institute (ATI), along with numerous other academic and industry partners.

TherapeUTex utilizes the expansive scientific expertise of the Principal Investigators and partners to generate and validate the properties of lead compounds using cell and animal models, in the following areas

1. The Science
• Scientific expertise, strategic design, and flexibility to provide individualized solutions
• Study design to develop intellectual property and commercialization opportunities
2. Animal Models
• Disease specific animal models for testing therapeutic efficacy, including oncology, lung inflammation and infectious diseases
• Customized animal models for special needs including administration by oral, buccal, inhalation, intravenous, Intramuscular dosing
• Evaluation and Analysis
• In vivo / In vitro target validation studies
• Tissue, dose response, metabolism and toxicology evaluation
• Imaging capabilities
• Pharmacokinetic and pharmacodynamic studies
• State of the art analytical technologies to characterize biological samples and dosage forms, including mass spectroscopy and immunohistochemistry
• Strategic study design to develop intellectual property and commercialization opportunities
3. Dose form development
• Tailored delivery system development, characterization, and optimization
• Comprehensive and custom development of novel and standard delivery modalities

Initially, TherapeUTex will focus on animal models in the areas of cancer, lung inflammation, including asthma, and infectious disease, and will facilitate data generation by processing and imaging tissue or cell samples. Additional animal models will be available and custom models can be developed upon request.

The work performed by TherapeUTex is based on the expertise of University faculty and its ability to build collaborations between academia, federally funded research, corporate grants and sponsored research.

Please see also our services and equipment page.

Mailing Address:

Drug Dynamics Institute
College of Pharmacy
The University of Texas
at Austin
1 University Station A1900
Austin, TX, USA
78712