Friday, January 6, 2012
7-9 pm Reception – “Eighteenth over Austin”
18th Floor Restaurant, Hilton Garden Inn Austin Downtown, 500 North IH 35
Saturday, January 7, 2012 (Pharmacy, PHR 3.106)
7:30 Packet Pickup & Continental Breakfast (outside PHR 3.106)
8:00 Welcome: Chris Whitman (Division of Medicinal Chemistry/University of Texas at Austin)
Session 1: Enzymes in Biosynthetic and Catabolic Pathways
Chair: Hung-wen (Ben) Liu
8:05 SUSAN C WANG
School of Molecular Biosciences, Washington State University, Pullman, WA
“Unusual Methyl Transfer Reactions in Microbial Biosynthesis"
8:35 DAVID P. BARONDEAU
Department of Chemistry, Texas A&M University, College Station, TX
"Frataxin-based Activation of the Human Fe-S Assembly Complex"
8:55 DONOVAN C. HAINES
Department of Chemistry, Sam Houston State University, Huntsville, TX
"A Single Residue with a Dramatic Impact on Substrate-induced Spin-State Change in P450BM-3"
9:15 BENJAMIN PHILMUS
Department of Chemistry, Texas A&M University, College Station, TX
"Studies into the Degradation of the Phytotoxin Toxoflavin. Degradation Through a Baeyer-Villiger Ring Expansion"
9:35 Coffee Break (Hallway outside PHR 3.106)
Session 2: Evolution, Regulation, and Mechanisms of Enzymes and Bioinformatics
Chair: Walt Fast
10:00 YAN JESSIE ZHANG
Department of Chemistry and Biochemistry, The University of Texas, Austin, TX
"Unmask the “CTD code” for Transcription Regulation"
10:30 CHAD MELANCON
Department of Chemistry & Chemical Biology, University of New Mexico, Albuquerque, NM
"Bioinformatics-Guided Natural Product Drug Discovery"
10:55 SIDDHESH KAMAT
Department of Chemistry, Texas A&M University, College Station, TX
"Decoding the C-P Lyase Pathway in Escherichia coli"
11:15 TYREL BYRAN
Department of Chemistry & Chemical Biology, University of New Mexico, Albuquerque, NM
"Criteria for Evolution of a Successful Enzyme Superfamily: Fold Fitness and Domain Dynamics Explored"
11:30 HELENA GAWESKA
Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, TX
"Mechanistic Studies of Berberine Bridge Enzyme"
11:45 WILLIAM C. SILVERS
Department of Chemistry, Louisiana State University, Baton Rouge, LA
"NQO1 Activated Latent Fluorophore for Live Cell Imaging"
12:00 Box Lunch (Second Floor Hallway, Pharmacy Building)
Session 3: Enzymology and Drug Design
Chair: Chris Whitman
1:15 PHILLIP A. SCHWARTZ
Oncology Research Unit, Pfizer Inc., La Jolla, CA
"Insights into Regulation of EGFR Oncogenic Signaling and Drug Resistance"
1:40 JOHN KOZARICH
ActivX Biosciences, Inc., La Jolla, CA
"Toward a Functional, Chemoproteomic Interrogation of Kinome and Nucleotide Binding Space"
Contact Information
Mailing Address:
Texas Enzyme
Mechanism Conference
c/o Chris Whitman
The University of Texas
at Austin
1 University Station
C0850
BME 6.202A
Austin, TX, USA
78712-0120
Email Address: enzyme@
uts.cc.utexas.edu
Phone:
1-512-471-6198
Abstracts due:
Dec. 12, 2011
Conference dates:
Jan.6-7, 2012
