THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC) POLICIES AND PROCEDURES MANUAL
Complete Manual - Adobe PDF File
SECTION 1: INTRODUCTION
1.0 Purpose and Scope of Manual
1.1 Mission Statement
1.2 OLAW and the Animal Welfare Assurance
1.3 USDA and the Animal Welfare Regulations
1.4 AAALAC Accreditation
SECTION 2: THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC)
2.0 Authority, Composition and Function
2.1 Authority
2.2 Committee Composition
2.3 Conflict of Interest and Confidentiality
2.4 Quorum Requirements
2.5 Functions of the IACUC
2.6 Liability
SECTION 3: IACUC RESEARCH PROPOSALS
3.0 Protocol Review
3.1 Protocol Review Criteria
3.2 Protocol Review Procedures
3.3 Categories of IACUC Actions
3.4 Review of Modifications to Approved Protocols
3.5 Alternatives – Replacement, Reduction, and Refinement
3.6 Minimization of Pain and Distress
SECTION 4: MONITORING OF APPROVED PROTOCOLS
4.0 The Annual Renewal
4.1 The Third Year Renewal
4.2 The Comparison of Protocols to Grants
SECTION 5: TRAINING IN THE USE OF ANIMALS IN RESEARCH
5.0 Training
5.1 Who should receive training?
5.2 IACUC Training Requirements
5.3 Education and Training of the New IACUC Members
5.4 Continuing Education Provided for the IACUC Members
SECTION 6: LABORATORY ANIMAL OCCUPATIONAL HEALTH PROGRAM
6.0 Laboratory Animal Occupational Health Program (LAOHP)
6.1 The IACUC’s Responsibility for Occupational Health and Safety
6.2 Role of the IACUC in the Occupational Health Program
6.3 Elements of the Occupational Health Program
6.4 Personnel Participation in the Laboratory Animal Occupational Health Program
6.5 Health Program Education and Training
SECTION 7: SEMIANNUAL PROGRAM REVIEW AND SITE INSPECTIONS
7.0 Semiannual Program Reviews and Facility Inspections
7.1 Staffing and Scheduling the Facility Inspections
7.2 Categories to be Inspected
7.3 Performing Inspections
7.4 Documentation
SECTION 8: ANIMAL WELFARE CONCERNS AND NONCOMPLIANCE SITUATIONS
8.0 Evaluation of Animal Care and Use Concerns
8.1 Methods for Reporting
8.2 IACUC Procedures for the Investigation of Animal Care and Use Concerns
8.3 Non-Compliance with IACUC Polices, Procedures, or Decisions
8.4 Consequences of Non-Compliance
SECTION 9: RECORDKEEPING
9.0 Maintaining IACUC Records
9.1 Minutes
9.2 Protocols
9.3 Other Records
Appendices
A. ARC Guideline: Requirements of Housing Mice
B. ARC Guideline: Requirements for Cage Identification
C. ARC Guideline: Animal Facility Access Policy
D. IACUC Guideline: Non-Human Primate Enrichment Guidelines
E. IACUC Guideline: Humane Euthanasia of Laboratory Animals
E- 1: Use of Carbon Dioxide for Rodent Euthanasia
E- 2: Use of Cervical Dislocation for Rodent Euthanasia
F. IACUC Guideline: Animal Use in Human Subject Study Environments