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The Office of Research Support (ORS) does not administer or oversee HOP policy 5-2011 or training related to the policy. ORS administers HOP policy 7-1210, “Promoting Objectivity in Research by Managing, Reducing or Eliminating Financial Conflicts of Interest” so if you conduct research and have:

  1. Not submitted a Financial Interest Disclosure (FID), you will need to complete mandatory training and file a FID. Instructions for completing these requirements are located at
  2. Previously submitted a FID, you are not required to complete additional training nor re-disclose the same information to comply with the UTS 180/HOP 5-2011 policy requirements.   However, you may have other responsibilities under that policy.

HOP policy 5-2011 QUESTIONS? Contact the Provost’s Office or call Mike Kerker, Associate Vice Provost at (512) 471-2694.

Policies, Procedures, and Guidelines

IACUC Guidelines  |  Handbook of Operating Procedures  |  ARC Guidelines 
EHS Guidelines  |  IACUC Handbook of Policies and Procedures

IACUC Guidelines

These guidelines have been written to assist faculty, staff, and students in performing vertebrate animal procedures in a humane manner and complying with pertinent regulatory requirements. Under some circumstances deviations from these procedures may be indicated but such variances must be approved in advance by the IACUC.

The University of Texas at Austin Revised Handbook of Operating Procedures (HOP)


Animal Resources Center (ARC) Guidelines

These guidelines have been written by Animal Resources Center veterinarians and staff to be used as a resource for faculty, staff, and students to provide guidance and best practices for animal users.

  • Facility Access
  • Cage Identification Requirements
  • Requirements for Housing Mice
  • Personal Protective Equipment (PPE) Requirements for Personnel Working with Non-Human Primate

Environmental Health & Safety (EHS) Guidelines

These guidelines have been written by Environmental Health & Safety staff to be used as a resource for faculty, staff, and students to provide guidance and best practices for animal users.

Controlled Substances
Principal Investigators (PIs) using controlled substances in their laboratory research (including research animals) are subject to extensive state and federal regulatory requirements.

Safety Guidelines for Field Researchers
Fieldwork is an important part of teaching and research at The University of Texas at Austin. Since fieldwork activities take you off campus, this guide is intended to help you plan and prepare for health and safety problems you might encounter in the field.


  • Standard Operating Procedure: Nanoparticles in Animals

The Institutional Animal Care and Use Committee Handbook of Policies And Procedures (IACUC/HOPP)

PDF IconComplete Handbook - Adobe PDF File

Section 1: Introduction

  • 1.0 Purpose and Scope of Manual
  • 1.1 Mission Statement
  • 1.2 Office of Laboratory Animal Welfare (OLAW)
    • 1.2.1 Animal Welfare Assurance
  • 1.3 United States Department of Agriculture (USDA)
    • 1.3.1 The Animal Welfare Act
      • Inclusions
      • Exemptions
      • Research Facilities
  • 1.4 Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC)

Section 2: The Institutional Animal Care and Use Committee

  • 2.0 Authority
  • 2.1 Committee Composition
  • 2.2 Conflict of Interest
  • 2.3 Confidentiality
  • 2.4 Quorum Requirements
  • 2.5 Functions of the IACUC
  • 2.6 Liability
  • 2.7 Use of Electronic Mail (Email) for Official Correspondence
  • 2.8 Making Recommendations to the Institutional Official

Section 3: IACUC Research Proposals

  • 3.0 Protocol Review
  • 3.1 General Scope of Review
  • 3.2 Specific Types of Activities
  • 3.3 Exemptions
  • 3.4 Who can be a Principal Investigator?
  • 3.5 Protocol Review Criteria
  • 3.6 Protocol Review Procedures
    • 3.6.1 Full Committee Review (FCR)
    • 3.6.2 Designated Member Review (DMR)
    • 3.6.3 Administrative Review (AR)
    • 3.6.4 Notification of Review Outcome
    • 3.6.5 Appeal of an IACUC Decision
  • 3.7 Required Principal Investigator Certifications
  • 3.8 Range of IACUC Actions
  • 3.9 Review of Modifications to Approved Protocols
    • REVISED 3.9.1 Significant Changes
    • REVISED 3.9.2 Non-Significant Changes
    • NEW 3.9.3 Veterinary consultation and protocol changes to address urgent humane issues
  • 3.10 Weekly DMR Docket
  • 3.11 Administrative Action on Termination of Reviewed (Pending/Not Yet Approved) Protocols and Amendments
  • 3.12 Minimization of Pain and Distress
    • 3.12.1 Assessing Pain and Distress
    • 3.12.2 Alleviation of Pain and Distress
  • 3.13 Guidance Documents
  • NEW 3.14 Non-UT Personnel

Section 4: Monitoring of Approved Protocols

  • 4.0 Continuing Review: The Annual Review
    • 4.0.1 Procedures for Conducting Annual Reviews
    • 4.0.2 The Purpose and Substance of Continuing Review
    • 4.0.3 Ethical Cost-Benefit Analysis
  • 4.1 The Third-Year Resubmission: de novo Review
    • 4.1.1 Procedures for Conducting Triennial Reviews
  • 4.2 Comparison of Protocols to Grants
    • 4.2.1 Verification of Protocol and Proposal Consistency
    • 4.2.2 Timing of Verification
    • 4.2.3 Protocol Amendments
    • 4.2.4 Managing Grant-Protocol Inconsistencies
  • 4.3 Post-Approval Monitoring (PAM)

Section 5: Training in the Humane Care and Use of Laboratory Animals

  • 5.0 Training
  • 5.1 Who Should Receive Training?
  • 5.2 Training Requirements for University Laboratory Animal Users
    • 5.2.1 AALAS Learning Library (ALL) Web-based Training Modules
    • 5.2.2 Enrollment in the Occupational Health Program-Laboratory Animal and Biomedical Services (OHP-LABS)
    • 5.2.3 Training Requirements for Personnel Working with Macaques
  • 5.3 Education and Training for IACUC Members
    • 5.3.1 New Member Orientation
    • 5.3.2 Continuing Education

Section 6: Occupational Health Program

  • 6.0 Laboratory Animal and Biomedical Services (OHP-LABS)
  • 6.1 The IACUC's Responsibility for Occupational Health and Safety
  • 6.2 Role of the IACUC in the Occupational Health Program
  • 6.3 Elements of the Occupational Health Program
  • 6.4 Participation in the Occupational Health Program
  • 6.5 Occupational Health Program Education and Training

Section 7: Semiannual Program Review and Facility Inspections

  • 7.0 Semiannual Reviews
  • 7.1 Program Review
  • 7.2 Facility Inspections
    • 7.2.1 Staffing and Scheduling the Facility Inspections
    • 7.2.2 Categories to be Inspected
    • 7.2.3 Performing Inspections
  • 7.3 Deficiency Correction Schedule
  • 7.4 Documentation

Section 8: Animal Welfare Concerns And Non-Compliance Situations

  • 8.0 Evaluation of Animal Care and Use Concerns
  • 8.1 Methods for Reporting
  • 8.2 Procedures for the Investigation of Animal Care and Use Concerns
    • 8.2.1 Initial Evaluation and Actions
    • 8.2.2 The Complaint Assessment Subcommittee
    • 8.2.3 Investigation
    • 8.2.4 Outcomes and Final Actions
  • 8.3 Non-Compliance with IACUC Protocol, Policies, Procedures, or Decisions
  • 8.4 Consequences of Non-Compliance
    • 8.4.1 Institutional Sanctions
    • 8.4.2 Suspension of Animal Activities
  • 8.5 Reporting Requirements
    • 8.5.1 Principal Investigator Reporting
    • 8.5.2 IACUC and IO Reporting
    • 8.5.3 Response to External Requests for Information

Section 9: Recordkeeping

  • 9.0 Maintaining IACUC Records
  • 9.1 Meeting Minutes
  • 9.2 Protocols
  • 9.3 Other Records
  • 9.4 Record Retention Policy at The University of Texas at Austin