Policies, Procedures, and Guidelines
IACUC Guidelines
These guidelines have been written to assist faculty, staff, and students in performing vertebrate animal procedures in a humane manner and complying with pertinent regulatory requirements. Under some circumstances deviations from these procedures may be indicated but such variances must be approved in advance by the IACUC.
Guidelines to Promote the Psychological Well-Being of Non-Human Primates- Guidelines for the Humane Euthanasia of Laboratory Animals
- Guidelines for the Use of Carbon Dioxide for Rodent Euthanasia
- Guidelines for the Use of Cervical Dislocation for Rodent Euthanasia
- Guidelines for Animal Use in Human Subject Study Environments
- Guidelines for Non-rodent Mammalian Surgical Procedures
- Guidelines for Survival Surgical Procedures in Rodent, Birds, and Cold-blooded Vertebrates
- Guidelines for Endpoint Monitoring and Humane Termination
- Guidelines for Maintenance of Tumors and Hybridomas in Rodents
- Guidelines for Safe Anesthetic Use
- Guidelines for the Transportation of Animals on The University of Texas at Austin Campus
- Guidelines for Blood Collection
- Guidelines for Tail Clipping Mice
- Guidelines for the Use of Adjuvants in Antibody Production
The University of Texas at Austin Revised Handbook of Operating Procudures (HOP)
Policy Number 11.B.3: USE OF ANIMALS IN RESEARCH AND TEACHING ACTIVITIES
ARC Guidelines
The Institutional Animal Care and Use Committee Handbook of Policies And Procedures (IACUC/HOPP)
Complete Handbook - Adobe PDF File
Section 1: Introduction
- 1.0 Purpose and Scope of Manual
- 1.1 Mission Statement
- 1.2 Office of Laboratory Animal Welfare (OLAW)
- 1.2.1 Animal Welfare Assurance
- 1.3 United States Department of Agriculture (USDA)
- 1.3.1 The Animal Welfare Act
- 1.3.1.1 Inclusions
- 1.3.1.2 Exemptions
- 1.3.1.3 Research Facilities
- 1.4 Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC)
Section 2: The Institutional Animal Care and Use Committee
- 2.0 Authority
- 2.1 Committee Composition
- 2.2 Conflict of Interest
- 2.3 Confidentiality
- 2.4 Quorum Requirements
- 2.5 Functions of the IACUC
- 2.6 Liability
- 2.7 Use of Electronic Mail (Email) for Official Correspondence
- 2.8 Making Recommendations to the Institutional Official
Section 3: IACUC Research Proposals
- 3.0 Protocol Review
- 3.1 General Scope of Review
- 3.2 Specific Types of Activities
- 3.3 Exemptions
- 3.4 Who can be a Principal Investigator?
- 3.5 Protocol Review Criteria
- 3.6 Protocol Review Procedures
- 3.6.1 Full Committee Review (FCR)
- 3.6.2 Designated Member Review (DMR)
- 3.6.3 Administrative Review (AR)
- 3.6.4 Notification of Review Outcome
3.7 Required Principal Investigator Certifications - 3.8 Range of IACUC Actions
- 3.9 Review of Modifications to Approved Protocols
- 3.9.1 Significant Changes
- 3.9.2 Non-Significant Changes
- 3.10 Weekly DMR Docket
- 3.11 Administrative Action on Termination of Reviewed (Pending/Not Yet Approved) Protocols and Amendments
- 3.12 Minimization of Pain and Distress
- 3.12.1 Assessing Pain and Distress
- 3.12.2 Alleviation of Pain and Distress
- 3.13 Guidance Documents
Section 4: Monitoring of Approved Protocols
- 4.0 Continuing Review: The Annual Review
- 4.0.1 Procedures for Conducting Annual Reviews
- 4.0.2 The Purpose and Substance of Continuing Review
- 4.0.3 Ethical Cost-Benefit Analysis
- 4.1 The Third-Year Resubmission: de novo Review
- 4.1.1 Procedures for Conducting Triennial Reviews
- 4.2 Comparison of Protocols to Grants
- 4.2.1 Verification of Protocol and Proposal Consistency
- 4.2.2 Timing of Verification
- 4.2.3 Protocol Amendments
- 4.2.4 Managing Grant-Protocol Inconsistencies
- 4.3 Post-Approval Monitoring
Section 5: Training in the Humane Care and Use of Laboratory Animals
- 5.0 Training
- 5.1 Who Should Receive Training?
- 5.2 Training Requirements for University Laboratory Animal Users
- 5.2.1 AALAS Learning Library (ALL) Web-based Training Modules
- 5.2.2 Enrollment in the Laboratory Animal and Biomedical Occupational Health Services Program (LABOHSP):
- 5.3 Education and Training for IACUC Members
- 5.3.1 New Member Orientation
- 5.3.2 Continuing Education
Section 6: Occupational Health Program
- 6.0 Laboratory Animal and Biomedical Services (LABOHSP)
- 6.1 The IACUC's Responsibility for Occupational Health and Safety
- 6.2 Role of the IACUC in the Occupational Health Program
- 6.3 Elements of the Occupational Health Program
- 6.4 Participation in the Occupational Health Program
- 6.5 Occupational Health Program Education and Training
Section 7: Semiannual Program Review and Facility Inspections
- 7.0 Semiannual Reviews
- 7.1 Program Review
- 7.2 Facility Inspections
- 7.2.1 Staffing and Scheduling the Facility Inspections
- 7.2.2 Categories to be Inspected
- 7.2.3 Performing Inspections
- 7.3 Deficiency Correction Schedule
- 7.4 Documentation
Section 8: Animal Welfare Concerns And Non-Compliance Situations
- 8.0 Evaluation of Animal Care and Use Concerns
- 8.1 Methods for Reporting
- 8.2 Procedures for the Investigation of Animal Care and Use Concerns
- 8.2.1 Initial Evaluation and Actions
- 8.2.2 The Complaint Assessment Subcommittee
- 8.2.3 Investigation
- 8.2.4 Outcomes and Final Actions
- 8.3 Non-Compliance with IACUC Protocol, Policies, Procedures, or Decisions
- 8.4 Consequences of Non-Compliance
- 8.4.1 Institutional Sanctions
- 8.4.2 Suspension of Animal Activities
- 8.5 Reporting Requirements
- 8.5.1 Principal Investigator Reporting
- 8.5.2 IACUC and IO Reporting
- 8.5.3 Response to External Requests for Information
Section 9: Recordkeeping
- 9.0 Maintaining IACUC Records
- 9.1 Meeting Minutes
- 9.2 Protocols
- 9.3 Other Records
- 9.4 Record Retention Policy at The University of Texas at Austin