Publications


Tipps ME, Lawshe JE, Ellington AD, and Mihic SJ. Identification of novel specific allosteric modulators of the glycine receptor using phage display. J Biol Chem. In press. (2010). PubMed

Welsh BT, Kirson D, Allen HM and Mihic SJ. Ethanol enhances taurine–activated glycine receptor function. Alcohol: Clin. Exp. Ther. In press. (2010). PubMed

Todorovic J, Welsh BT, Bertaccini EJ, Trudell JR and Mihic SJ. Disruption of an inter-subunit electrostatic bond is a critical step in glycine receptor activation. Proc Natl Acad Sci U S A. 107:7987-92. (2010). PubMed

McCracken LM, Trudell JR, Goldstein BE, Harris RA, Mihic SJ. Zinc enhances ethanol modulation of the alpha1 glycine receptor. Neuropharmacol. 58:676-81 (2010). PubMed

Welsh BT, Goldstein BE, Mihic SJ. Single channel analysis of ethanol enhancement of glycine receptor function. J Pharmacol Exp Ther. 330:198-205 (2009). PubMed

Dupre ML, Broyles JM and Mihic SJ. Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation. Brain Res. 1152:1-9 (2007). PubMed

Roberts MT, Phelan R, Erlichman BS, Pillai RN, Ma L, Lopreato GF and Mihic SJ. Occupancy of a single anesthetic binding pocket is sufficient to enhance glycine receptor function. J. Biol. Chem. 281:3305-11 (2006). PubMed

Lopreato GF, Banerjee P and Mihic SJ. Amino acids in transmembrane domain two influence anesthetic enhancement of serotonin-3A receptor function. Mol. Brain Res. 118:45-51 (2003). PubMed

Lopreato GF, Phelan R, Borghese CM, Beckstead MJ and Mihic SJ. Inhaled drugs of abuse enhance serotonin-3 receptor function. Drug Alcohol Depend. 70:11-15 (2003). PubMed

Beckstead MJ, Phelan R, Trudell JR, Bianchini MJ and Mihic SJ. Anesthetic and ethanol effects on spontaneously opening glycine receptor channels. J. Neurochem 82:1343-1351 (2002). PubMed

Beckstead MJ, Phelan R and Mihic SJ. Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor function. J. Biol. Chem. 276:24959-24964 (2001). PubMed

Beckstead MJ, Weiner JL, Eger 2nd EI, Gong DH and Mihic SJ. Glycine and gamma-aminobutyric acidA receptor function is enhanced by inhaled drugs of abuse. Mol. Pharmacol. 57:1199-1205 (2000). PubMed

Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA and Harrison NL. Sites of alcohol and volatile anaesthetic action on GABA-A and glycine receptors. Nature 389:385-389 (1997). PubMed