PostDoc Opportunities

Postdoctoral positions are available to study the physiology and drug regulation of neurons in the brain reward circuit, i.e., the mesolimbic dopamine system.

We are currently working on the following three projects.

  1. Calcium signaling in the brain reward circuit
    This project investigates the roles of calcium signaling in regulating excitability and plasticity of neurons in the mesolimbic dopaminergic system and in addiction-related learning and memory processes. (Neuron 62:826-838, 2009; J Neurosci 30:6689-6699, 2010; Neuron 77:335-345, 2013)
  2. Alcohol action on neurons in the brain reward circuit
    The goal of this project is to identify key cellular and molecular substrates underlying alcohol dependence/addiction in the mesolimbic dopaminergic system. (Neuropsychopharmacology 36:993-1002, 2011; J Neurosci 31:5205-5212, 2011)
  3. Local microcircuits in the striatum
    This project investigates the mechanisms controlling the activity of identified types of neurons in the striatum at the local microcircuit level. (J Neurosci 28:8682-8690, 2008; J Neurosci 6:2697-708, 2013)

Techniques used in the lab include:

  • brain slice electrophysiology
  • confocal calcium imaging
  • flash photolysis
  • optogenetics
  • rodent behavior
  • immunohistochemistry

Previous experience in at least one of the following techniques is desirable:

  • in vitro/in vivo electrophysiology
  • calcium imaging
  • stereotaxic procedures in rodent brain
  • rodent behavior

PhD or MD is required. The initial appointment will be 2 years with a possibility of extension. The salary will be commensurate with experience.

If interested, please contact Hitoshi Morikawa.