UT Grad Cat, 97-99


Contents

Chapter 1

Chapter 2

Chapter 3

Chapter 4

Chapter 5

Appendix


 


 


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19 August 1997



   Chapter Four - Fields of Study

 Pharmacy
 About the Program  Graduate Studies Committee  Courses


The faculty has approval to offer the following courses in the academic years 1997-1998 and 1998-1999; however, all courses are not taught each semester or summer session. Students should consult the Course Schedule to determine which courses and topics will be offered during a particular semester or summer session. The Course Schedule may also reflect changes that have been made to the courses listed here since this catalog was published.

Unless otherwise stated below, each course meets for three lecture hours a week for one semester.

Pharmacy: PHR

380D. Structure-Activity Relationships and Mechanisms of Action.
Pharmacy 340D and 380D may not both be counted. Prerequisite: Graduate standing.

380E. Communication Skills for Scientists.
Designed to teach oral communication skills and the basics of scientific writing, including grant applications and manuscripts. Offered on the credit/no credit basis only. Only one of the following may be counted: Pharmacy 160H, 260H, 360H, 280E, 380E. Prerequisite: Graduate standing and consent of instructor.

380F. Biomedical Pharmacology I.
Drug classifications, mechanisms of drug action, drug side effects/adverse reactions in humans, the use of drugs in research. Neuroscience 380F and Pharmacy 380F may not both be counted. Prerequisite: Graduate standing and a background in physiology and organic chemistry.

180J, 280J, 380J. Advanced Pharmaceutics: Laboratory Problems.
Three, six, or nine laboratory hours a week for one semester. May be repeated for credit. Prerequisite: Graduate standing.

180M, 280M, 380M. Advanced Pharmaceutics.
The equivalent of one, two, or three lecture hours a week for one semester. May be repeated for credit when the topics vary. Prerequisite: Graduate standing.

380N. Biomedical Pharmacology II.
Fundamental concepts of pharmacology, including molecular mechanisms of drug action, absorption, distribution and elimination, tolerance, dependence, mutagenesis, teratogenesis, and carcinogenesis. Pharmacy students must take this course on the letter-grade basis. Neuroscience 380N and Pharmacy 380N may not both be counted. Prerequisite: Graduate standing, and Pharmacy 380F or consent of instructor.

380Q. Advanced Pharmaceutical Processing.
Didactic and laboratory exposure to pharmaceutical processes used in the design, development, and optimization of drug delivery systems. Emphasis on equipment and machinery used in pharmaceutical manufacturing of these dosage forms, with discussion of other issues, such as technology transfer and scale-up. Six lecture hours and three laboratory hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing in pharmacy.

280U. Case Studies in Emerging Infections.
Case studies in the analysis and therapeutic control of recurring, cycling, and newly emerging infectious disease. Two lecture hours a week for one semester. Prerequisite: Completion of the pharmacotherapeutics sequence.

381C. Microbial Transformations in Pharmaceutical Chemistry.
Application of microorganisms for conducting specific type-reactions of general application; emphasis on methodology, transformations by structural classes, and specific reactions. Prerequisite: Graduate standing and consent of instructor.

381D. Product Development.
Applications of physical-chemical principles to the formulation and development of stable and bioavailable drug delivery systems. Pharmacy 351H and 381D may not both be counted. Prerequisite: Graduate standing in the College of Pharmacy.

381E. Advanced Hospital Pharmacy.
An in-depth analysis of the operation and administration of the institutional pharmacy and its relationship to the total functioning of the hospital. Prerequisite: Graduate standing.

381G. Advanced Manufacturing Pharmacy.
Physical-mechanical properties of compacts, drugs, and polymers. Properties of biodegradable and nonbiodegradable polymers in pharmaceutical formulations. Process validation and pilot plant scale-up. Prerequisite: Graduate standing.

181J, 281J, 381J. Advanced Pharmacy Administration: Laboratory Problems.
Three, six, or nine laboratory hours a week for one semester. May be repeated for credit. Prerequisite for students who entered the professional pharmacy curriculum before the spring semester 1995-1996: Graduate standing; prerequisite for students entering in spring 1995-1996 or later: Graduate standing and consent of instructor.

181M, 281M, 381M. Advanced Pharmacy Administration.
One, two, or three lecture hours a week for one semester. May be repeated for credit. Prerequisite: Graduate standing.

381N. Third-Party Payment Systems and Managed Health Care.
Examination of the classic and contemporary literature on third-party payment systems in health care, with emphasis on pharmacy-related issues. Attention to the advantages, disadvantages, and effects of these systems and of managed health care approaches used by many third-party payers. Prerequisite: Graduate standing.

381P. Health Care Administration.
Introduction to the United States health care system and its relationship to pharmacy; comparison with health care in other countries. Prerequisite: Graduate standing.

381R. Preclinical Sciences I.
Designed both to accomplish an assessment of student readiness for a rigorous doctoral curriculum and to develop academic preparedness; emphasizes preclinical science fundamentals. Offered on the credit/no credit basis only. Prerequisite: Graduate standing.

382C. Chemistry of Natural Products.
The use of microorganisms in type-reactions in synthetic and natural products chemistry and as model systems for predicting mammalian drug metabolism and toxicity; emphasis on methodologies, transformations by structural classes, and control of specific biotransformations. Pharmacy 332C and 382C may not both be counted. Prerequisite: Graduate standing and consent of instructor.

382L. Drug Literature Evaluation.
Prepares the student for efficient utilization, critical evaluation, and clinical application of the current drug literature. Two lecture hours and three laboratory hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

682M. Advanced Biopharmaceutical Analysis.
Advanced methods for the determination, isolation, and identification of drugs and their metabolites in biological media. Three lecture hours a week for two semesters. Prerequisite: Graduate standing.

382N. Computer-Assisted Kinetics.
Quantitative and simulation treatment of kinetics through computer technology. Topics include protein binding and utilization of program packages such as NONLIN, RSSL, CSMP, SAAM 23, and AUTOAN. Prerequisite: Graduate standing, and Pharmacy 345 or the equivalent.

382R. Recent Advances in Pharmaceutics.
Presentation of topics of current research interest in physical pharmacy, biopharmaceutics, and pharmacokinetics. Prerequisite: Graduate standing.

382S. Advanced Biopharmaceutics.
Provides the student with a more comprehensive background in biopharmaceutics and mathematical techniques used in pharmacokinetics. Pharmacy 362H and 382S may not both be counted. Prerequisite: Graduate standing and Pharmacy 345.

382T. Principles of Neuroscience I.
A proseminar covering the core material on essential topics in neuroscience from the molecular to the systems level. Only one of the following may be counted: Biomedical Engineering 382T, Kinesiology 382T, 688QA, Neuroscience 382T, Pharmacy 382T, 688QA, Psychology 382T, 688QA, Zoology 382T, 688QA. Prerequisite: Graduate standing and consent of instructor.

382V. Pharmaceutical Biotechnology.
Applications of protein, oligonucleotide, and related molecules as therapeutic agents: stability, formulation, kinetics, dynamics. Prerequisite: Graduate standing, Chemistry 339K, and Pharmacy 341, 141K, 345, and 145K.

283C. Pharmaceutical Sciences I.
A systematic presentation of pharmacologic agents based on drug-group classification; emphasis on pharmacological mechanisms of action and toxicity. Covers basic pharmacological principles. Two lecture hours a week for one semester. Prerequisite: Graduate standing.

483D. Neuropharmacological Mechanisms.
Four lecture hours a week for one semester. Only one of the following may be counted: Neuroscience 483D, Pharmacy 473M, 483D. Prerequisite: Graduate standing.

283L. Clinical Skills Laboratory.
Introduction to patient assessment techniques and to the skills needed to provide innovative patient care services. One lecture hour and three laboratory hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

383M. Pharmacogenetics.
The study of those combined genetic and pharmacological factors that give rise to many unexpected, untoward, and idiosyncratic drug reactions. Prerequisite: Graduate standing, and Pharmacy 473M or the equivalent or consent of instructor.

383N. Solution Theory and Disperse Systems.
The theory and technology of solutions and heterogeneous systems; applications of scientific principles to the design of pharmaceutical products; a study of factors influencing physical chemical characteristics, stability, and biopharmaceutical activity of solutions and coarse dispersions; review of recent literature. Prerequisite: Graduate standing and consent of instructor.

383P. Advanced Pharmacokinetics.
Study of the kinetics of absorption, distribution, metabolism, and excretion of drugs in the intact organism. Prerequisite: Graduate standing, and Pharmacy 345 or the equivalent.

383R. Rate Processes in Pharmaceutical Systems.
A study of decomposition and stabilization of drug molecules in solutions and in solid dosage forms; principles of kinetics and diffusion as applied to pharmaceutical systems. Prerequisite: Graduate standing and consent of instructor.

283S. Clinical Toxicology.
An advanced study of toxicological, pharmaceutical, and pharmacological principles underlying the management of chemical poisoning. Includes analysis of selected cases. Two lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

383T. Principles of Neuroscience II.
Continuation of Pharmacy 382T; a proseminar covering the core material on essential topics in neuroscience from the molecular to the systems level. Only one of the following may be counted: Biomedical Engineering 383T, Kinesiology 383T, 688QB, Neuroscience 383T, Pharmacy 383T, 688QB, Psychology 383T, 688QB, Zoology 383T, 688QB. Prerequisite: Graduate standing, Pharmacy 382T (or 688QA), and consent of instructor.

284K. Advanced Toxicology.
An organ system approach to advanced topics in general toxicology. Two lecture hours a week for one semester. Required of pharmacology majors. Prerequisite: Graduate standing, and some background in pharmacology or consent of instructor.

384N. Social Issues in Pharmacy.
In-depth analysis of the social and behavioral issues that affect medication use, using the content, theories, and methodologies associated with patient compliance research. Prerequisite: Graduate standing.

284R. Advances in Molecular Pharmacology.
A molecular pharmacological perspective on recent advances in cloning, sequencing, expression, function, and regulation of cell surface receptors. Two lecture hours a week for one semester. May be repeated for credit when the topics vary. Prerequisite: Graduate standing; and Pharmacy 473K, 283C (or 483C), 385N, 382T (or 688QA), 392C, or the equivalent, or consent of instructor.

384S. Introduction to Epidemiology and Pharmacoepidemiology.
Principles of epidemiology; descriptive, analytic, and clinical epidemiology; epidemiologic perspective for health care management; epidemiology and the public policy process; pharmacoepidemiology. Prerequisite: Graduate standing, admission to the professional pharmacy curriculum, and consent of instructor.

185D. Responsible Conduct of Science.
Ethical considerations in the conduct of science, including issues of animal welfare, data analysis, fraud, publications, misconduct, intellectual property, grants, peer review, and mentor responsibility. One lecture hour a week for one semester. Offered on the credit/no credit basis only. Neuroscience 185D and Pharmacy 185D may not both be counted. Prerequisite: Graduate standing.

385L. Clinical Pharmacokinetics.
In-depth analysis of pharmacotherapeutic regimens, using complex mathematical models. May not be counted by students with credit for Pharmacy 185K, 285L, or 185M. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

385N. Neuropharmacology.
A fundamental course in basic autonomic pharmacology and neuropharmacology, emphasizing methods and neurotransmitter characteristics. Pharmacy 275K and 385N may not both be counted. Required of pharmacology majors. Prerequisite: Graduate standing, and Pharmacy 473M or the equivalent.

386E. Enzymes and DNA as Chemical Targets for Drug Action.
Chemical and biochemical approaches for studying the interaction of small molecules with enzymes and DNA. Emphasis on chemical aspects of these problems, with some discussion of techniques in molecular biology useful in studies of drug-receptor interactions. Prerequisite: Graduate standing.

386F. The Organic Chemistry of Drug Design and Drug Action.
The chemical aspects of drug design, development, and action, with emphasis on the molecular mechanisms involved. Pharmacy 366F and 386F may not both be counted. Prerequisite: Graduate standing in pharmacy, chemistry, or biochemistry, or graduate standing and consent of instructor.

186J, 286J, 386J. Advanced Medicinal Chemistry: Laboratory Techniques.
Modern laboratory techniques used in medicinal and natural products chemistry. Three, six, or nine laboratory hours a week for one semester. May be repeated for credit. Prerequisite: Graduate standing.

186K, 286K, 386K. Advanced Medicinal Chemistry.
The equivalent of one, two, or three lecture hours a week for one semester. May be repeated for credit. Prerequisite: Graduate standing.

386M. Pharmaceutical Distribution.
An in-depth study of the channels of distribution, drug product selection, promotion, pricing, legal and professional environments of the pharmaceutical industry, and pharmacy practice. Prerequisite: Graduate standing.

286N. Advances in the Pharmacological Treatment of Central Nervous System Diseases.
Recent advances in the treatment of Parkinson's disease, schizophrenia, depression and bipolar disorder, and Alzheimer's disease. Two lecture hours a week for one semester. May be repeated for credit when the topics vary. Prerequisite: Graduate standing; and Pharmacy 473K, 283C (or 483C), 385N, 382T (or 688QA), 392C, or the equivalent, or consent of instructor.

386S. Molecular Biology of the Nervous System.
Study of the structure and function of macromolecules in the brain. Only one of the following may be counted: Neuroscience 386S, Pharmacy 336S, 386S. Prerequisite: Graduate standing, and a course in biochemistry or consent of instructor.

286T. Advanced Nuclear Magnetic Resonance Spectroscopy in Bioorganic Chemistry: Theory and Applications.
Problem-based applications of nuclear magnetic resonance to biological chemistry. Advanced study of NMR spectroscopy, including physical principles, pulse methods, and experimental design. Two lecture hours a week for one semester. Prerequisite: Graduate standing, two semesters of organic chemistry, one semester of physics, and consent of instructor.

186U. Advanced Nuclear Magnetic Resonance Spectroscopy Laboratory.
Students use high-field nuclear magnetic resonance instrumentation and computer routines to learn techniques and problems in state-of-the-art three-dimensional macromolecular structure determination. Three laboratory hours a week for one semester. Prerequisite: Graduate standing; and credit or registration for Pharmacy 286T, advanced nuclear magnetic resonance training, or consent of instructor.

286V. Advanced Nuclear Magnetic Resonance Spectroscopy in Bioorganic Chemistry: Macromolecular Applications.
Expansion of nuclear magnetic resonance concepts discussed in Pharmacy 286T, with emphasis on problems in three-dimensional structure determination in biological macromolecules (carbohydrates, proteins, nucleic acids). Two lecture hours a week for one semester. Prerequisite: Graduate standing, and Pharmacy 286T or consent of instructor.

386W. Stereochemical Aspects of Synthetic Medicinal Chemistry.
Methods for preparing stereochemically defined compounds for drug development; emphasis on regioselective and stereoselective reactions, use of stereochemically defined compounds from nature, and preparative separation technology. Pharmacy 368P and 386W may not both be counted. Prerequisite for students who entered the professional pharmacy curriculum before the spring semester 1995-1996: Graduate standing; and eight hours of organic chemistry and one semester of physical chemistry, or consent of instructor; prerequisite for students entering in spring 1995-1996 or later: Graduate standing and Pharmacy 385E, 285F, and 185P.

387C. Advanced Institutional Pharmacy Management.
Management principles, practices, and problems, applied to the pharmacy organization within a health care institution. Prerequisite: Graduate standing and consent of instructor.

387G. Research Design and Grant Writing.
Training in the methodology of experiment design and the composition of research grant applications. Offered on the credit/no credit basis only. Prerequisite: Graduate standing and completion of written cumulative examinations in preparation for candidacy for the doctoral degree.

687K. Methods in Neuropharmacology.
Nine laboratory hours a week for two semesters. Neuroscience 687KA and Pharmacy 687KA may not both be counted; Neuroscience 687KB and Pharmacy 687KB may not both be counted. Prerequisite: For 687KA, graduate standing and Pharmacy 380E (or 280E); for 687KB, Pharmacy 687KA.

487P. Pathophysiology I.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Four lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

387R. Pathophysiology II.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

587S. Pathophysiology III.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Five lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

387T. Pathophysiology IV.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

387U. Pathophysiology V.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

387V. Pathophysiology VI.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

287W. Pathophysiology VII.
Provides the student with a sound knowledge and comprehension of functional changes that accompany disease states. Two lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

388C. Introductory Bioorganic Chemistry.
Survey of high-field NMR techniques and their applications in bioorganic chemistry. Applications include biosynthesis of natural products, enzyme mechanisms, and drug-DNA interactions. Prerequisite: Graduate standing and Chemistry 391.

388D. Advanced Bioorganic Chemistry.
Topics include biosynthesis of natural products, mechanisms of enzymes, and drug-DNA interactions. May be repeated for credit when the topics vary. Prerequisite: Graduate standing.

188J, 288J, 388J. Advanced Pharmacology: Laboratory Problems.
Three, six, or nine laboratory hours a week for one semester. May be repeated for credit. Prerequisite: Graduate standing.

188K, 288K, 388K. Advanced Pharmacology.
The equivalent of one, two, or three lecture hours a week for one semester. May be repeated for credit when the topics vary. Prerequisite: Graduate standing.

488U. Pathophysiology and Pharmacotherapeutics of Psychiatric Disorders.
Provides the student with a sound knowledge and comprehension of diagnostic criteria, altered physiologic states, and therapeutic principles of psychiatric illnesses. Four lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

389C. Pharmacy Association Management.
An introduction to the principles involved in managing pharmacy associations. Pharmacy 329C and 389C may not both be counted. Prerequisite: Graduate standing and consent of instructor.

689D. Pharmacy Association Management Residency.
Experience working in a pharmacy association, including active involvement in some managerial aspect of the association. Twenty laboratory hours a week for one semester. Pharmacy 629D and 689D may not both be counted. Prerequisite: Graduate standing and consent of instructor.

189E. Advanced Pharmacotherapeutics of Musculoskeletal Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic regimens used in the treatment of diseases involving the musculoskeletal system. One lecture hour a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

289F. Advanced Pharmacotherapeutics of Neurological Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic principles used in treating neurological diseases. Two lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

189G. Advanced Pharmacotherapeutics of Endocrine Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic regimens used in treating endocrine disorders. One lecture hour a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

189H. Advanced Pharmacotherapeutics of Gastrointestinal Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic regimens used in treating gastrointestinal disorders. One lecture hour a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

289J. Advanced Pharmacotherapeutics of Cardiovascular Disorders.
Provides the student with a sound knowledge and comprehension of contemporary pharmacotherapeutic regimens used in treating cardiovascular diseases. Two lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

189L. Advanced Pharmacotherapeutics of Renal Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic regimens used in treating renal diseases and associated disorders. One lecture hour a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

189M. Advanced Pharmacotherapeutics of Pulmonary Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic regimens used in treating pulmonary diseases. One lecture hour a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

189N. Advanced Pharmacotherapeutics of Reproductive Disorders.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic regimens used in treating reproductive disorders and problems in conception. One lecture hour a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

289P. Advanced Pharmacotherapeutics of Infectious Diseases I.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic principles used in treating infectious diseases. Two lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

189Q. Seminar in Alcohol Studies.
Presentations and discussion of current research topics in alcohol studies. One lecture hour a week for one semester. Offered on the credit/no credit basis only. Prerequisite: Graduate standing and consent of instructor.

389S. Advanced Pharmacotherapeutics of Hematology/Oncology.
Provides the student with a sound knowledge and comprehension of contemporary therapeutic principles used in treating hematologic and malignant diseases. Offered on the letter-grade basis only. Prerequisite: Graduate standing.

390J. Pharmacy Administration Data Analysis.
Statistical analysis of research data using the computer and various statistical software programs. Nine laboratory hours a week for one semester. Prerequisite: Graduate standing and Pharmacy 390K.

390K. Experimental Design and Research Methodology in Pharmacy Administration.
Principles and procedures of experimental design and research methodology; preexperimental, true, and quasi-experimental designs, reliability, validity, data collection, methods and simulation techniques. Prerequisite: Graduate standing.

490N. Biochemical Toxicology.
Discussion of the mechanisms of selected drugs and toxicants. Four lecture hours a week for one semester. Prerequisite: Graduate standing and Pharmacy 284K (or 384K).

390P. Experimental Design and Statistics in Pharmacology.
Classical and experimental design and analysis of variance as it relates to pharmacology and neuroscience research. Practical aspects of design and analysis. Nonlinear regression and its use in model fitting and hypothesis testing. Nine laboratory hours a week for one semester. Neuroscience 390P and Pharmacy 390P may not both be counted. Prerequisite: Graduate standing.

290R, 390R. Special Problems in Pharmacotherapy.
Individual supervision of research problems in the clinical pharmacy sciences, including pharmacokinetics, pharmacodynamics, efficacy, safety, and pharmaceutical care. For 290R, five laboratory hours a week for one semester; for 390R, nine laboratory hours a week for one semester. May be repeated for credit when the topics vary. Prerequisite: Graduate standing and consent of instructor.

291K, 391K, 491K. Clinical Rotation I.
Analysis of pharmacotherapeutic practices, evaluation of drug use, and synthesis of rational drug regimens in the context of patient care. Six, nine, or twelve laboratory hours a week for one semester. Offered on the credit/no credit basis only. Prerequisite: Graduate standing and consent of the supervising professor.

291L, 391L, 491L. Clinical Rotation II.
Analysis of pharmacotherapeutic practices, evaluation of drug use, and synthesis of rational drug regimens in the context of patient care. Six, nine, or twelve laboratory hours a week for one semester. Offered on the credit/no credit basis only. Prerequisite: Graduate standing; Pharmacy 291K, 391K, or 491K; and consent of the supervising professor.

291M, 391M, 491M. Clinical Rotation III.
Analysis of pharmacotherapeutic practices, evaluation of drug use, and synthesis of rational drug regimens in the context of patient care. Six, nine, or twelve laboratory hours a week for one semester. Offered on the credit/no credit basis only. With consent of the graduate adviser, may be repeated for credit. Prerequisite: Graduate standing; Pharmacy 291L, 391L, or 491L; and consent of the supervising professor.

392C. Pharmacological Mechanisms I.
Advanced course on drug mechanisms; review of literature on several organ systems. Prerequisite: Graduate standing, and Pharmacy 473K or consent of instructor.

693. Research in Pharmacy.
The equivalent of three lecture hours a week for two semesters. May be repeated for credit when the topics vary. May not be counted toward the master's degree. Prerequisite: For 693A, graduate standing; for 693B, Pharmacy 693A.

Topic 1: Research in Medicinal Chemistry.

Topic 2: Research in Pharmaceutics.

Topic 3: Research in Pharmacology.

Topic 4: Research in Pharmacy.

Topic 5: Research in Pharmacy Administration.

Topic 6: Research in Toxicology.

493D. Computer-Assisted Drug Design.
Overview of theory and application of methods useful for computer-assisted drug design, such as molecular orbital calculations, molecular mechanics and dynamics, conformational search, CoMFA, and three-dimensional searching. Hands-on experience with professional-level software and hardware. Two lecture hours and three laboratory hours a week for one semester. Prerequisite: Graduate standing, consent of instructor, and an undergraduate course in physical chemistry.

393Q. Health-Related Quality of Life Measurement.
Terms, concepts, procedures, methods, problems, and strengths associated with health-related quality of life (HRQOL) research. Prerequisite: Graduate standing.

394D. Interfacial Phenomena in Pharmaceutics.
Phase interfaces, monolayers, bilayers, and nonlamellar surfactant assemblies in terms of thermodynamics, dynamic properties, stability, permeability, and measurement methods. Prerequisite: Graduate standing and a course in physical chemistry.

394F. Pharmacoeconomics.
Terms, concepts, procedures, methods, problems, and strengths associated with pharmacoeconomics. Offered on the letter-grade basis only. Pharmacy 393T and 394F may not both be counted. Prerequisite: Admission to the PharmD program, and completion of the pharmacotherapeutics sequence or consent of instructor and the dean.

394L. Stereochemical and Regiochemical Aspects of Metabolism.
Stereochemical concepts and conventions defined in the context of xenobiotic (principally drug) metabolism; methods for conducting and interpreting stereochemical and regiochemical metabolism studies. Pharmacy 334L and 394L may not both be counted. Prerequisite: Graduate standing and consent of instructor.

395C. Clinical Pharmacology and Therapeutics.
Application of pharmacologic and pharmacokinetic principles to drug therapy management in family primary care nursing. Prerequisite: Graduate standing.

395D. Pathophysiology.
Structure, function, and mechanisms of disease production in human organ systems. Nursing 396C and Pharmacy 395D may not both be counted. Prerequisite: Graduate standing.

296. Seminar in Pharmacy.
The equivalent of one lecture hour a week for two semesters. Offered on the credit/no credit basis only. Students in the Doctor of Pharmacy program may take Pharmacy 296A for independent credit. Prerequisite: Graduate standing in pharmacy.

396C. Synthetic Medicinal Chemistry.
An organic chemistry approach to drug synthesis based on chemical structures desired or needed for biological intervention. Focus on synthetic methodology useful in carbocyclic and heterocyclic chemistry. Prerequisite: Graduate standing; and one of the following: Chemistry 386J, 396M, an upper-division course in organic chemistry, or consent of instructor.

396F. Advanced Pharmacotherapy.
Designed to provide the student with a sound knowledge and comprehension of contemporary therapeutic regimens. Offered on the letter-grade basis only. Prerequisite: Admission to the PharmD program, completion of the pharmacotherapeutics sequence or consent of instructor and the dean, and concurrent enrollment in Pharmacy 296P.

396M. Medicinal Chemistry: General Principles, Pharmacological Classification, and Mechanism of Action.
Introduction to medicinal chemistry, covering drug classes according to their pharmacological classification, structural class, and mechanism of action. Prerequisite: Graduate standing and undergraduate coursework in organic chemistry and biochemistry.

196T. Seminar in Toxicology.
Presentations and discussion of current research topics in toxicology. One lecture hour a week for one semester. Offered on the credit/no credit basis only. Prerequisite: Graduate standing, and admission to the Toxicology Training Program or consent of instructor.

397C. Pharmacy and Health Care Economics.
The economist's approach to pharmacy and health care issues, its insights and disadvantages. Prerequisite: Graduate standing.

397D. Pharmacy Human Resource Management.
The elements of supervising pharmacists and technicians in pharmacy environments. Prerequisite: Graduate standing.

397E. Financial Management for Pharmacy Managers.
Concepts, principles, and theoretical foundations of financial statements, with emphasis on the pharmacy manager's understanding of accounting procedures and the use of financial statements. Prerequisite: Graduate standing.

397F. Analytical Methods in Pharmacy Management.
Computer analytic methods used to derive budget projections, manage purchasing data, and analyze operations research methods of creating and managing projects and systems. Three lecture hours and three laboratory hours a week for one semester. Prerequisite: Graduate standing.

397G. Advanced Community Pharmacy Management.
Location analysis, purchasing and financing, layout and design of a pharmacy; merchandising, marketing, and advertising. Prerequisite: Graduate standing.

397J. Advanced Problems in Pharmacy Management.
Current problems in community and institutional pharmacy management. Students analyze and prepare a report on a problem in pharmacy management. Twelve laboratory hours a week for one semester. Prerequisite: Graduate standing.

397K. Communication Skills for Pharmacy Managers.
Written and oral communication skills and techniques for pharmacists at the managerial level. Prerequisite: Graduate standing.

397M. Drug Design and Synthetic Strategy.
A multiperspective approach to modern concepts in drug design and synthetic strategy, including the use of computers and artificial intelligence, with appropriate examples. Prerequisite: Graduate standing; and Chemistry 386J, Pharmacy 396M, or consent of instructor.

698. Thesis.
The equivalent of three lecture hours a week for two semesters. Offered on the letter-grade basis only. Prerequisite: For 698A, graduate standing in pharmacy and consent of the graduate adviser; for 698B, Pharmacy 698A.

698K. Hospital Pharmacy Residency.
Not less than 1,920 hours of satisfactorily supervised work in an approved hospital pharmacy. A report of the activities of the internship must meet the approval of the student's supervisory committee. The equivalent of three lecture hours a week for two semesters. Prerequisite: For 698KA, graduate standing in pharmacy and a Bachelor of Science in Pharmacy; for 698KB, Pharmacy 698KA.

398R. Master's Report.
Preparation of a report to fulfill the requirement for the master's degree under the report option. The equivalent of three lecture hours a week for one semester. Offered on the letter-grade basis only. Prerequisite: Graduate standing in pharmacy, admission to the Option II program for the Master of Science in Pharmacy degree, and consent of the graduate adviser.

398T. Supervised Teaching in Pharmacy.
Teaching under close supervision of the faculty; weekly group meetings with the appropriate instructor; individual consultations; semester reports. Prerequisite: Graduate standing and consent of instructor.

399R, 699R, 999R. Dissertation.
Offered on the letter-grade basis only. Prerequisite: Admission to candidacy for the doctoral degree.

399W, 699W, 999W. Dissertation.
Offered on the letter-grade basis only. Prerequisite: Pharmacy 399R, 699R, or 999R.


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Graduate Catalog

Contents
Chapter 1: Graduate Study
Chapter 2: Admission and Registration
Chapter 3: Degree Requirements
Chapter 4: Fields of Study
Chapter 5: Members of Graduate Studies Committees
Appendix: Course Abbreviations


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