Please direct all questions about the flag proposal process to the Center for the Core Curriculum.
College of Pharmacy
Please describe specifically the quantitative skills students will learn and apply in the course.
This course focuses on the mathematical modeling of the fate of drugs in the body. Along with the associated laboratory (PHR 171P) students apply the basic principles of integral and differential calculus to the complex modeling of single and multi-compartment models associated with basic pharmacokinetics. At each stage of growing complexity, the focus shifts to the impact of this modeling on direct patient care, in which the modeling allows for disease-state specific and patient-specific care in terms of drug dosing and therapeutic monitoring.
On what kinds of real-world problems will students use quantitative skills?
As indicated above students will be applying the pharmacokinetic modeling to direct patient care (e.g., how do you dose a drug that is excreted by the kidneys if the patient only has 60% of their renal function left). This is exactly the type of practical, real-world application they will face in practice.
Describe typical assignments related to Quantitative Reasoning.
In both the lecture and lab, students will be examining cases in which various parameters affecting drug absorption, distribution, metabolism, and excretion. As an example, they would need to be able to calculate appropriate dosing modifications for renal impairment, liver dysfunction, obesity, etc. Cases are consistent with the complexity presented in the course text “Applied Clinical Pharmacokinetics” by Bauer.
Please explain how at least one-half of the course grade is based on content relat