Professor Johnson's lab is interested in how ribosomes are transported from their site of assembly in the nucleus to their site of function in the cytoplasm. And once in the cytoplasm, how are they "unpackaged" and activated for translation. They use yeast as a model eukaryotic organism because it offers a greater "tool kit" of reagents and techniques than practically any other system available. In their work, they combine genetic, cell biology, molecular biology and biochemical techniques. Although they do not work directly on disease, their work reveals highly conserved fundamental cellular pathways that are important for understanding cell function and providing context for disease-related research. Recently, they have been collaborating on understanding how defects in the ribosome lead to T-cell acute lymphoblastic leukemia.
Undergraduate projects will be tailored to the student's ability and range from genetic screens to biochemical purification of proteins.
Affiliated Research Units
Now that you've used EUREKA to identify a faculty member whose research interests match your own, read about getting involved in research at The University of Texas at Austin.
The Office of Undergraduate Research recommends that you attend an info session before contacting faculty members about research opportunities. We'll cover the steps to getting involved, tips for contacting faculty, funding possibilities, and options for course credit.
If you aren't able to attend an info session, contact the Office of Undergraduate Research to schedule an appointment with an advisor.