Center for Perceptual Systems

Nicholas Priebe


Associate Professor

Nicholas Priebe

Contact

Biography


Nicholas Priebe received his Ph.D. in Physiology from the University of California, San Francisco in 2001 after studying adaptation in motion-selective neurons with Stephen Lisberger. Dr. Priebe was a postdoctoral fellow with David Ferster at Northwestern University, investigating the mechanisms underlying neronal responses in primary vusual cortex. The massive expansion of cerebral cortex is a hallmark of the human brain. We know that the cortex plays an essential role in our perceptions and actions. Sensory inputs from the periphery are transformed in the cortex, allowing us to generate appropriate motor outputs. Dr. Priebe's lab studies the cortical circuitry and the computations that underlie such transformations, using vision as a model system. In visual cortex, neuronal circuitry performs the computations that extract motion, orientation and depth information about the visual environment from subcortical inputs. For example, primary visual cortex (V1) is the cortical location in which information from the two eyes is first integrated, ultimately allowing us to perceive depth in our visual field. By understanding the circuitry that underlies these kinds of computations, we gain insight into similar computations that occur throughout cortex.

Publications


Benjamin Scholl, Sari Andoni and Nicholas J. Priebe.
Functional characterization of spikelet activity in the primary visual cortex
J. Physiol. in press.

 

Benjamin Scholl, Jagruti J. Pattadkal, Geoff A. Dilly, Nicholas J. Priebe* and Boris V. Zemelman*.
Local integration accounts for weak selectivity of mouse neocortical parvalbumin interneurons
Neuron. 2015 87:424-436.

 

Jude F. Mitchell*, Nicholas J. Priebe* and Cory T. Miller.
Motion dependence of smooth pursuit eye movements in the marmoset
J. Neurophys. 2015 113(10): 3954-3960.

 

Nicholas J. Priebe and Aaron W. McGee.
Mouse vision as a gateway for understanding how experience shapes neural circuits
Front Neural Circuits. 2014.

 

Andrew Y.Y. Tan*, Yuzhi Chen*, Benjamin Scholl*, Eyal Seidemann' and Nicholas J. Priebe'.
Sensory stimulation shifts visual cortex from synchronous to asynchronous states
Nature. 2014 509(7499):226-229.

 

Benjamin Scholl, Andrew Y.Y. Tan and Nicholas J. Priebe.
Strabismus disrupts binocular synaptic integration in primary visual cortex
J. Neurosci. 2013 33(43):17108-17122.

 

Andrew Y.Y. Tan, Sari Andoni and Nicholas J. Priebe.
A spontaneous state of weakly correlated synaptic excitation and inhibition in visual cortex
Neuroscience 2013 247: 364-375.
Brian Source Code

 

Benjamin Scholl, Andrew Y.Y. Tan, Joe Corey and Nicholas J. Priebe.
Emergence of orientation selectivity in the mammalian visual pathway
J. Neurosci. 2013 33(26):10616-10624.

 

Benjamin Scholl, Johannes Burge, and Nicholas J. Priebe.
Binocular Integration and Disparity Selectivity in Mouse Primary Visual Cortex
J. Neurophys. 2013 109(12):3013-3024.

 

Nicholas J. Priebe and David Ferster
Mechanisms of neuronal computation in mammalian visual cortex
Neuron. 2012 75(2):194-208.

 

 

Courses


Semester      Course      Unique No.         Title 

2014 Fall      NEU 365L      56765           Neurobiology Laboratory

2013 Fall      Bio 365L        50875           Neurobiology Laboratory 

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